User profiles for Otavio Berwanger

Professor Otavio Berwanger

George Institute for Global Health and Imperial College London
Verified email at georgeinstitute.org.uk
Cited by 23574

Association between administration of systemic corticosteroids and mortality among critically ill patients with COVID-19: a meta-analysis

…, DC Angus, D Annane, LCP Azevedo, O Berwanger… - Jama, 2020 - jamanetwork.com
Importance Effective therapies for patients with coronavirus disease 2019 (COVID-19) are
needed, and clinical trial data have demonstrated that low-dose dexamethasone reduced …

Effect of dexamethasone on days alive and ventilator-free in patients with moderate or severe acute respiratory distress syndrome and COVID-19: the CoDEX …

BM Tomazini, IS Maia, AB Cavalcanti, O Berwanger… - Jama, 2020 - jamanetwork.com
Importance Acute respiratory distress syndrome (ARDS) due to coronavirus disease 2019 (COVID-19)
is associated with substantial mortality and use of health care resources. …

[HTML][HTML] Antithrombotic therapy after acute coronary syndrome or PCI in atrial fibrillation

…, J Li, O Averkov, MC Bahit, O Berwanger… - … England Journal of …, 2019 - Mass Medical Soc
Background Appropriate antithrombotic regimens for patients with atrial fibrillation who have
an acute coronary syndrome or have undergone percutaneous coronary intervention (PCI) …

Effect of tocilizumab on clinical outcomes at 15 days in patients with severe or critical coronavirus disease 2019: randomised controlled trial

…, FG Zampieri, FR Machado, RD Lopes, O Berwanger… - bmj, 2021 - bmj.com
Objective To determine whether tocilizumab improves clinical outcomes for patients with
severe or critical coronavirus disease 2019 (covid-19). Design Randomised, open label trial. …

[HTML][HTML] Hydroxychloroquine with or without Azithromycin in Mild-to-Moderate Covid-19

…, RD Lopes, FR Machado, O Berwanger - … England Journal of …, 2020 - Mass Medical Soc
Background Hydroxychloroquine and azithromycin have been used to treat patients with
coronavirus disease 2019 (Covid-19). However, evidence on the safety and efficacy of these …

[HTML][HTML] Therapeutic versus prophylactic anticoagulation for patients admitted to hospital with COVID-19 and elevated D-dimer concentration (ACTION): an open-label …

…, A Avezum, AB Cavalcanti, O Berwanger - The Lancet, 2021 - thelancet.com
Background COVID-19 is associated with a prothrombotic state leading to adverse clinical
outcomes. Whether therapeutic anticoagulation improves outcomes in patients hospitalised …

[HTML][HTML] Aspirin in patients undergoing noncardiac surgery

…, T VanHelder, P Paniagua, O Berwanger… - … England Journal of …, 2014 - Mass Medical Soc
Background There is substantial variability in the perioperative administration of aspirin in
patients undergoing noncardiac surgery, both among patients who are already on an aspirin …

[HTML][HTML] Tofacitinib in patients hospitalized with Covid-19 pneumonia

…, LV Rizzo, T Koncz, O Berwanger - … England Journal of …, 2021 - Mass Medical Soc
Background The efficacy and safety of tofacitinib, a Janus kinase inhibitor, in patients who
are hospitalized with coronavirus disease 2019 (Covid-19) pneumonia are unclear. Methods …

Association between administration of IL-6 antagonists and mortality among patients hospitalized for COVID-19: a meta-analysis

…, FR MACHADO, RG ROSA, O Berwanger - Jama, 2021 - jamanetwork.com
Importance Clinical trials assessing the efficacy of IL-6 antagonists in patients hospitalized
for COVID-19 have variously reported benefit, no effect, and harm. Objective To estimate the …

Association of postoperative high-sensitivity troponin levels with myocardial injury and 30-day mortality among patients undergoing noncardiac surgery

…, DI Sessler, A Kurz, W Szczeklik, O Berwanger… - Jama, 2017 - jamanetwork.com
Importance Little is known about the relationship between perioperative high-sensitivity
troponin T (hsTnT) measurements and 30-day mortality and myocardial injury after noncardiac …