A murine model of pulmonary damage induced by lipopolysaccharide via intranasal instillation

RJ Szarka, N Wang, L Gordon, PN Nation… - Journal of immunological …, 1997 - Elsevier
This study examines the intranasal instillation of lipopolysaccharide (LPS) into BALB/c mice
causing acute pulmonary damage, due to neutrophil infiltration and sepsis. A dose response …

Intestinal protozoa and epithelial cell kinetics, structure and function

A Buret, DG Gall, PN Nation, ME Olson - Parasitology today, 1990 - Elsevier
Intestinal protozoa are not only common enteric pathogens in the tropics but also the high
incidence of infection among immunocompromised patients in northern countries has evoked …

Virus-encoded serine proteinase inhibitor SERP-1 inhibits atherosclerotic plaque development after balloon angioplasty

…, K Graham, W Etches, L Boshkov, PN Nation… - Circulation, 1996 - Am Heart Assoc
… All surgical procedures and care of rabbits were according to the University of Alberta Animal
Welfare Committee and national guidelines. In the initial pilot study, MonoQ-purified SERP-…

Immunoprophylactic potential of cloned Shiga toxin 2 B subunit

…, RJ Read, K Vander Helm, PN Nation… - The Journal of …, 2001 - academic.oup.com
The Shiga toxins Stx1 and Stx2 contribute to the development of enterohemorrhagic O157:
H7 Escherichia coli—mediated colitis and hemolytic-uremic syndrome in humans. The Stx2 B …

Novel neonatal piglet models of surgical short bowel syndrome with intestinal failure

JM Turner, PW Wales, PN Nation… - Journal of pediatric …, 2011 - journals.lww.com
… In this study the minimum time any piglet may have been receiving PN support, … of PN support
between groups 1 and 3, whereas only 1 piglet from group 2 was able to wean from PN, on …

Novel long‐acting GLP‐2 analogue, FE 203799 (apraglutide), enhances adaptation and linear intestinal growth in a neonatal piglet model of short bowel syndrome …

…, M Lansing, P Wizzard, PN Nation… - Journal of Parenteral …, 2019 - Wiley Online Library
… Mucosal hyperplasia was assessed by measurement of villus height and crypt depth,
performed by a board-certified animal pathologist (PN Nation) blinded to treatment group. Height …

[HTML][HTML] Cellular mechanism of action of 2-nitroimidazoles as hypoxia-selective therapeutic agents

…, F Mashayekhi, D Macdonald, PN Nation… - Redox Biology, 2022 - Elsevier
Solid tumours are often poorly oxygenated, which confers resistance to standard treatment
modalities. Targeting hypoxic tumours requires compounds, such as nitroimidazoles (NIs), …

Chronic eosinophilic dermatitis: a manifestation of a multisystemic, eosinophilic, epitheliotropic disease in five horses

JSN Wilkie, JA Yager, PN Nation… - Veterinary …, 1985 - journals.sagepub.com
A generalized, chronic, progressive, exfoliative dermatitis in five horses is described.
Histologically, the lesion is characterized by a superficial and deep perivascular dermatitis which is …

Inhibition of transplant vasculopathy in a rat aortic allograft model after infusion of anti-inflammatory viral serpin

…, L Liu, C Icton, D Klironomos, L Fan, PN Nation… - Circulation, 2000 - Am Heart Assoc
… by university laboratory animal ethics committees and conform to national guidelines. …
Research Council of Canada, the National Cancer Institute of Canada, Biogen Inc, and Viron Inc. …

A preclinical study of the safety and efficacy of Occlusin™ 500 artificial embolization device in sheep

RJ Owen, PN Nation, R Polakowski, JA Biliske… - Cardiovascular and …, 2012 - Springer
… on Animal Care and the National Institutes of Health. Animals were housed under conditions
consistent with all provincial and national regulations and received standard medical care …