User profiles for Pasquale Giordano

Pasquale Giordano

Barts Health NHS Trust & Queen Mary University London
Verified email at londoncolorectal.org
Cited by 4113

Transanal hemorrhoidal dearterialization: a systematic review

P Giordano, J Overton, F Madeddu… - Diseases of the colon …, 2009 - journals.lww.com
PURPOSE: Transanal hemorrhoidal dearterialization consists of a Doppler-guided ligation
of the distal branches of the rectal arteries. The aim of this review is to assess the current …

[HTML][HTML] Modern management of anal fistula

E Limura, P Giordano - World Journal of Gastroenterology: WJG, 2015 - ncbi.nlm.nih.gov
Ideal surgical treatment for anal fistula should aim to eradicate sepsis and promote healing
of the tract, whilst preserving the sphincters and the mechanism of continence. For the simple …

Long-term outcomes of stapled hemorrhoidopexy vs conventional hemorrhoidectomy: a meta-analysis of randomized controlled trials

P Giordano, G Gravante, R Sorge, L Ovens… - Archives of …, 2009 - jamanetwork.com
Objectives To assess the long-term results of stapled hemorrhoidopexy (SH) compared with
conventional hemorrhoidectomy (CH) and to define the role of SH in the treatment of …

Simple cutaneous advancement flap anoplasty for resistant chronic anal fissure: a prospective study

P Giordano, G Gravante, P Grondona… - World journal of …, 2009 - Wiley Online Library
Pasquale Giordano had full access to all of the data in the study and takes responsibility
for the integrity of the data and the accuracy of the data analysis. Presented in part at the …

The HubBLe Trial: haemorrhoidal artery ligation (HAL) versus rubber band ligation (RBL) for symptomatic second-and third-degree haemorrhoids: a multicentre …

…, P Skaife, A Agarwal, P Giordano… - Health Technology …, 2016 - eprints.whiterose.ac.uk
BACKGROUND: Optimal surgical intervention for low-grade haemorrhoids is unknown.
Rubber band ligation (RBL) is probably the most common intervention. Haemorrhoidal artery …

[PDF][PDF] S‐adenosyl methionine regulates ubiquitin‐conjugating enzyme 9 protein expression and sumoylation in murine liver and human cancers

…, K Ramani, RM Pascale, J Xu, P Giordano… - …, 2012 - Wiley Online Library
Ubiquitin‐conjugating enzyme 9 (Ubc9) is required for sumoylation and is overexpressed in
several malignancies, but its expression in hepatocellular carcinoma (HCC) is unknown. …

[PDF][PDF] MAT2B‐GIT1 interplay activates MEK1/ERK 1 and 2 to induce growth in human liver and colon cancer

…, H Yang, ML Tomasi, I Tomasi, P Giordano… - …, 2013 - Wiley Online Library
Methionine adenosyltransferase 2B (MAT2B) encodes for two variant proteins (V1 and V2)
that promote cell growth. Using in‐solution proteomics, GIT1 (G Protein Coupled Receptor …

Mechanical bowel preparation for colorectal surgery: a meta-analysis on abdominal and systemic complications on almost 5,000 patients

…, R Caruso, SM Andreani, P Giordano - International journal of …, 2008 - Springer
Background Several studies concluded that mechanical bowel preparation (MBP) does not
confer any advantage on reducing the anastomotic leak rate or wound infections. The aim of …

Previous sphincter repair does not affect the outcome of repeat repair

P Giordano, A Renzi, J Efron, P Gervaz… - Diseases of the colon …, 2002 - journals.lww.com
PURPOSE: As many as 60 percent of patients present with recurrent symptoms of fecal
incontinence after anterior overlapping anal sphincter repair. The aim of this study was to assess …

Polyamine and methionine adenosyltransferase 2A crosstalk in human colon and liver cancer

…, M Ryoo, A Skay, I Tomasi, P Giordano… - Experimental cell …, 2013 - Elsevier
Methionine adenosyltransferase (MAT) is an essential enzyme that is responsible for the
biosynthesis of S-adenosylmethionine (SAMe), the principal methyl donor and precursor of …