Malignant hyperthermia (MH) causes neurological, liver, and kidney damage and death in
humans and major economic losses in the swine industry. A single point mutation in the …

Flavonoids, including isoflavones, are natural components in our diet and, with the burgeoning
interest in alternative medicine, are increasingly being ingested by the general population…

Despite major advances in modern drug discovery and development, the number of new
drug approvals has not kept pace with the increased cost of their development. Increasingly, …

Aldehydes are organic compounds that are widespread in nature. They can be formed
endogenously by lipid peroxidation (LPO), carbohydrate or metabolism ascorbate autoxidation, …

Dietary polyphenolics in fruits, vegetables, wines, spices and herbal medicines have beneficial
antioxidant, anti-inflammatory and anticancer effects. However, we have observed that …

… Author links open overlay panel Jalal Pourahmad a , Peter J O‘Brien b , Farzaneh Jokar a ,
… ROS formation and cytotoxicity induced by added H 2 O 2 or generated by the intracellular …

Rapid scavenging of the model stable radical cation, ABTS •+ , has been applied to screen
for the antioxidant activity of flavonoids. The reaction follows two distinct phases. For …

The B vitamins are water-soluble vitamins required as coenzymes for enzymes essential for
cell function. This review focuses on their essential role in maintaining mitochondrial …

Studies have been made on the kinetics, products and properties of liver supernatant-catalyzed
GSH oxidation by linoleic acid hydroperoxide (LAHPO). It was found that an enzymic …

Tea phenolic acids and catechins containing gallic acid moieties are most abundant in
green tea, and various medical benefits have been proposed from their consumption. In the …