Chronic pain is associated with reduced brain gray matter and impaired cognitive ability. In
this longitudinal study, we assessed whether neuroanatomical and functional abnormalities …

Background Non-randomised trials have reported benefits of kyphoplasty in patients with
cancer and vertebral compression fractures (VCFs). We aimed to assess the efficacy and safety …

Painful degeneration of soft tissues accounts for high socioeconomic costs. Tissue engineering
aims to provide biomimetics recapitulating native tissues. Biocompatible thermoplastics …

Study design Systematic review. Objectives The aims of this systematic review were: (1) to
determine the most commonly used methods for assessing pedicle screw placement accuracy…

Intervertebral disc degeneration ( IVD ) can result in chronic low back pain, a common
cause of morbidity and disability. Inflammation has been associated with IVD degeneration, …

Porous titanium‐nickel (PTN) implants represent an alternative to traditional intervertebral
fusion cages. Indeed, PTN materials possess interconnecting pores with cell capillarity …

Calcification is a pathological process that may lead to impairment of nutrient supply and
disc metabolism in degenerative and scoliotic intervertebral discs (IVDs). The purpose of this …

Curcumin and o-Vanillin cleared senescent intervertebral disc (IVD) cells and reduced the
senescence-associated secretory phenotype (SASP) associated with inflammation and back …

Objective: Spontaneous spinal epidural hematoma (SSEH) manifests from blood accumulating
in the epidural space, compressing the spinal cord and leading to acute neurological …

Study Design. Retrospective cohort study of the prospective collected American College of
Surgeons National Surgical Quality Improvement Program database. Objective. The aim of …