We used 14 easily measured biologic and clinical variables to develop a simple scoring
system reflecting the risk of death in ICU patients. The simplified acute physiology score (SAPS) …

Brain tumor initiating cells (BTICs) contribute to the genesis and recurrence of gliomas. We
examined whether the microglia and macrophages that are abundant in gliomas alter BTIC …

Astrocytic tumors account for 42% of childhood brain tumors, arising in all anatomical regions
and associated with neurofibromatosis type 1 (NF1) in 15%. Anatomical site determines …

The hepatitis C virus (HCV) genome shows remarkable sequence variability, leading to the
classification of at least six major genotypes, numerous subtypes and a myriad of …

BACKGROUND The authors have developed a new method of drug delivery into the brain
using implantable biodegradable microspheres. In this study, this method was used to …

Over the last decades microvascular decompression (MVD) has been established as the
curative treatment of the primary Hemifacial Spasm (HFS), proven to be linked in almost all …

Chronic pain is a disabling disease with limited treatment options. While animal models have
revealed important aspects of pain neurobiology, therapeutic translation of this knowledge …

1260 emergency admissions to the intensive-care units (ICUs) of five USA and seven
French tertiary-care hospitals were surveyed by means of a standard severity-of-illness …

Intramedullary abscesses of the spinal cord are uncommon. Most of them occur in association
with heart, pulmonary or urogenital infections. We report two cases of intramedullary …

Background In the pediatric population, awake craniotomy began to be used for the resection
of brain tumor located close to eloquent areas. Some specificities must be taken into …