Osteoblast‐like cells from human subchondral osteoarthritic bone demonstrate an altered phenotype in vitro: Possible role in subchondral bone sclerosis

…, JP Pelletier, P Ranger… - … : Official Journal of …, 1998 - Wiley Online Library
Objective Osteoarthritis (OA) is accompanied by subchondral bone sclerosis. The present
study was undertaken to determine whether osteoblast‐like cells in patients with OA show an …

In-home telerehabilitation compared with face-to-face rehabilitation after total knee arthroplasty: a noninferiority randomized controlled trial

…, H Corriveau, F Marquis, F Cabana, P Ranger… - JBJS, 2015 - journals.lww.com
Background: The availability of less resource-intensive alternatives to home visits for rehabilitation
following orthopaedic surgeries is important, given the increasing need for home care …

Peroxisome proliferator–activated receptor γ activators inhibit interleukin‐1β–induced nitric oxide and matrix metalloproteinase 13 production in human chondrocytes

…, JP Pelletier, F Mineau, P Ranger… - Arthritis & …, 2001 - Wiley Online Library
Objective To determine the effects of peroxisome proliferator–activated receptor γ (PPARγ)
agonists on interleukin‐1 (IL‐1) induction of nitric oxide (NO) and matrix metalloproteinase 13 …

The increased synthesis of inducible nitric oxide inhibits IL-1ra synthesis by human articular chondrocytes: possible role in osteoarthritic cartilage degradation

JP Pelletier, F Mineau, P Ranger, G Tardif… - Osteoarthritis and …, 1996 - Elsevier
The degradation of osteoarthritic (OA) cartilage is likely related to the synthesis and the
release of catabolic factors by chondrocytes. Nitric oxide (NO) has recently been suggested as …

[HTML][HTML] Cost analysis of in-home telerehabilitation for post-knee arthroplasty

…, H Corriveau, F Marquis, F Cabana, P Ranger… - Journal of medical …, 2015 - jmir.org
Background: Rehabilitation provided through home visits is part of the continuum of care
after discharge from hospital following total knee arthroplasty (TKA). As demands for …

Interleukin 17 (IL-17) induces collagenase-3 production in human osteoarthritic chondrocytes via AP-1 dependent activation: differential activation of AP-1 members …

…, JA Di Battista, P Reboul, P Ranger… - The Journal of …, 2002 - jrheum.org
OBJECTIVE: In osteoarthritic (OA) synovial fluid, many proinflammatory cytokines coexist
and stimulate chondrocytes. As interleukin 17 (IL-17) is a catabolic cytokine, we explored its …

Patient satisfaction with in-home telerehabilitation after total knee arthroplasty: results from a randomized controlled trial

…, F Marquis, F Cabana, ÉL Belzile, P Ranger… - Telemedicine and e …, 2017 - liebertpub.com
Background and Introduction: Telerehabilitation after total knee arthroplasty (TKA) is supported
by strong evidence on the effectiveness of such intervention and from a cost-benefit point …

Expression and regulation of microsomal prostaglandin E synthase-1 in human osteoarthritic cartilage and chondrocytes.

…, J Martel-Pelletier, JP Pelletier, P Ranger… - The Journal of …, 2005 - jrheum.org
OBJECTIVE: Elevated production of prostaglandin E2 (PGE2) plays an important role in the
pathogenesis of arthritis. Recently, an inducible microsomal prostaglandin E synthase-1 (…

Production of lipid peroxidation products in osteoarthritic tissues: new evidence linking 4‐hydroxynonenal to cartilage degradation

B Morquette, Q Shi, P Lavigne, P Ranger… - … : Official Journal of …, 2006 - Wiley Online Library
Objective The lipid peroxidation product 4‐hydroxynonenal (HNE) is prominently produced
in osteoarthritic (OA) synovial cells, but its specific contribution to cartilage destruction is not …

4-Hydroxynonenal induces apoptosis in human osteoarthritic chondrocytes: the protective role of glutathione-S-transferase

…, H Fahmi, Q Shi, P Lavigne, P Ranger… - Arthritis research & …, 2008 - Springer
Introduction 4-Hydroxynonenal (HNE) is one of the most abundant and reactive aldehydes
of lipid peroxidation products and exerts various effects on intracellular and extracellular …