User profiles for Prachi Patel

Prachi Patel

Columbia University
Verified email at columbia.edu
Cited by 172

[PDF][PDF] Distinct signaling of coreceptors regulates specific metabolism pathways and impacts memory development in CAR T cells

…, L Guo, SE McGettigan, AD Posey, PR Patel… - Immunity, 2016 - cell.com
Chimeric antigen receptors (CARs) redirect T cell cytotoxicity against cancer cells, providing
a promising approach to cancer immunotherapy. Despite extensive clinical use, the …

The impact of coronavirus disease 2019 (COVID-19) on healthcare-associated infections in 2020: A summary of data reported to the National Healthcare Safety …

…, V Pattabiraman, RY Konnor, PR Patel… - Infection Control & …, 2022 - cambridge.org
Objectives:To determine the impact of the coronavirus disease 2019 (COVID-19) pandemic
on healthcare-associated infection (HAI) incidence in US hospitals, national- and state-level …

Induction of resistance to chimeric antigen receptor T cell therapy by transduction of a single leukemic B cell

…, DE Ambrose, M Klichinsky, O Shestova, PR Patel… - Nature medicine, 2018 - nature.com
We report a patient relapsing 9 months after CD19-targeted CAR T cell (CTL019) infusion
with CD19 – leukemia that aberrantly expressed the anti-CD19 CAR. The CAR gene was …

[HTML][HTML] Enhancing CAR T cell persistence through ICOS and 4-1BB costimulation

…, AD Posey Jr, C Shaw, A Wing, T Da, PR Patel… - JCI insight, 2018 - ncbi.nlm.nih.gov
Successful tumor eradication by chimeric antigen receptor–expressing (CAR-expressing) T
lymphocytes depends on CAR T cell persistence and effector function. We hypothesized that …

Rational development and characterization of humanized anti–EGFR variant III chimeric antigen receptor T cells for glioblastoma

…, J Scholler, T Ohkuri, A Kosaka, PR Patel… - Science translational …, 2015 - science.org
Chimeric antigen receptors (CARs) are synthetic molecules designed to redirect T cells to
specific antigens. CAR-modified T cells can mediate long-term durable remissions in B cell …

Ibrutinib enhances chimeric antigen receptor T-cell engraftment and efficacy in leukemia

JA Fraietta, KA Beckwith, PR Patel… - Blood, The Journal …, 2016 - ashpublications.org
Anti-CD19 chimeric antigen receptor (CAR) T-cell therapy is highly promising but requires
robust T-cell expansion and engraftment. A T-cell defect in chronic lymphocytic leukemia (CLL…

Reducing Ex Vivo Culture Improves the Antileukemic Activity of Chimeric Antigen Receptor (CAR) T Cells

…, RS O'Connor, JA Fraietta, PR Patel… - Cancer immunology …, 2018 - AACR
The success of chimeric antigen receptor (CAR)–mediated immunotherapy in acute
lymphoblastic leukemia (ALL) highlights the potential of T-cell therapies with directed cytotoxicity …

Continued increases in the incidence of healthcare-associated infection (HAI) during the second year of the coronavirus disease 2019 (COVID-19) pandemic

…, RY Konnor, DT Kuhar, A Nkwata, PR Patel… - Infection Control & …, 2023 - cambridge.org
Data from the National Healthcare Safety Network were analyzed to assess the impact of
COVID-19 on the incidence of healthcare-associated infections (HAI) during 2021. …

Acute exposure to ZnO nanoparticles induces autophagic immune cell death

…, DT Gracias, JL Hope, CJ Stairiker, PR Patel… - …, 2015 - Taylor & Francis
The increasing risk of incidental exposure to nanomaterials has led to mounting concerns
regarding nanotoxicity. Zinc oxide nanoparticles (ZnO NPs) are produced in large quantities …

Cortical encoding of melodic expectations in human temporal cortex

GM Di Liberto, C Pelofi, R Bianco, P Patel, AD Mehta… - Elife, 2020 - elifesciences.org
Humans engagement in music rests on underlying elements such as the listeners’ cultural
background and interest in music. These factors modulate how listeners anticipate musical …