[HTML][HTML] Advances in immunotherapy for melanoma: a comprehensive review

…, G Fabbrocini, B Bardhi, A Sinani, RA Guzman - Mediators of …, 2017 - hindawi.com
Melanomas are tumors originating from melanocytes and tend to show early metastasis
secondary to the loss of cellular adhesion in the primary tumor, resulting in high mortality rates. …

Hormones and mammary carcinogenesis in mice, rats, and humans: a unifying hypothesis.

S Nandi, RC Guzman, J Yang - Proceedings of the National …, 1995 - National Acad Sciences
An attempt has been made to put forward a unifying hypothesis explaining the role hormones
play in the genesis of mammary cancers of different phenotypes and genotypes in mice, …

Cell transplantation therapy for stroke

T Bliss, R Guzman, M Daadi, GK Steinberg - Stroke, 2007 - Am Heart Assoc
No treatment currently exists to restore lost neurological function after stroke. A growing
number of studies highlight the potential of stem cell transplantation as a novel therapeutic …

Mono-iodoacetate-induced histologic changes in subchondral bone and articular cartilage of rat femorotibial joints: an animal model of osteoarthritis

RE Guzman, MG Evans, S Bove… - Toxicologic …, 2003 - journals.sagepub.com
Osteoarthritis (OA) is a degenerative joint disease characterized by joint pain and a progressive
loss of articular cartilage. Studies to elucidate the pathophysiology of OA have been …

[HTML][HTML] Discovery and characterization of a novel inhibitor of matrix metalloprotease-13 that reduces cartilage damage in vivo without joint fibroplasia side effects

…, WH Roark, M Wilson, K Datta, R Guzman… - Journal of biological …, 2007 - ASBMB
Matrix metalloproteinase-13 (MMP13) is a Zn 2+ -dependent protease that catalyzes the
cleavage of type II collagen, the main structural protein in articular cartilage. Excess MMP13 …

Rivaroxaban with or without aspirin in patients with stable peripheral or carotid artery disease: an international, randomised, double-blind, placebo-controlled trial

…, M HARTLEIB, R GUZMAN, R BOURGEOIS… - The Lancet, 2018 - thelancet.com
Background Patients with peripheral artery disease have an increased risk of cardiovascular
morbidity and mortality. Antiplatelet agents are widely used to reduce these complications. …

HIV prevalence, risk behaviors, health care use, and mental health status of transgender persons: implications for public health intervention.

K Clements-Nolle, R Marx, R Guzman… - American journal of …, 2001 - ncbi.nlm.nih.gov
OBJECTIVES: This study described HIV prevalence, risk behaviors, health care use, and
mental health status of male-to-female and female-to-male transgender persons and …

Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice

AS Tsukamoto, R Grosschedl, RC Guzman, T Parslow… - Cell, 1988 - cell.com
Transcriptional activation of the in&l gene by proviral insertion mutations is thought to be a key
step in mammary tumor induction by the mouse mammary tumor virus (MMTV). To test this …

Bioavailability of lead to juvenile swine dosed with soil from the Smuggler Mountain NPL site of Aspen, Colorado

…, E Hoffman, WJ Brattin, RE Guzman… - Toxicological …, 1997 - academic.oup.com
Bioavailability of lead (Pb) has become an issue in quantifying exposure of sensitive
populations and, where necessary, establishing cleanup levels for contaminated soil. Immature …

HST photometry of dwarf elliptical galaxies in coma, and an explanation for the alleged structural dichotomy between dwarf and bright elliptical galaxies

AW Graham, R Guzmán - The Astronomical Journal, 2003 - iopscience.iop.org
As part of a research program exploring how and why dwarf elliptical (dE) galaxies depart
from the fundamental plane defined by luminous elliptical (E) galaxies, we have analyzed …