The biochemical response to ursodeoxycholic acid (UDCA)—so‐called “treatment response”—strongly
predicts long‐term outcome in primary biliary cholangitis (PBC). Several long‐…

The prevalence of hepatitis B and hepatitis C in immigrant communities is unknown. Immigrants
from south Asia are common in England and elsewhere, and the burden of viral hepatitis …

The hepatorenal syndrome (HRS) is the development of renal failure in patients with severe
liver disease in the absence of any other identifiable cause. Patients with hepatorenal …

Sepsis is a common complication of cirrhosis with a high mortality. In this study, we have
investigated some of the pathways that may be involved in tissue injury and death. Bile duct-…

The lack of a simple assay for the quantification of S-nitrosothiols in complex biological
matrices has hampered our understanding of their contribution to normal physiology and …

Background. Tenofovir disoproxil fumarate (TDF) is an established nucleotide analogue in
the treatment of chronic hepatitis B. Bone mineral density loss has been described in TDF-…

… Identical stimulation was sufficient to increase mean recovery time in another bs mutant,
easily shocked, indicating that this method may have general applicability (R. Marley and RA …

The mechanisms that facilitate animal magnetoreception have both fascinated and confounded
scientists for decades and its precise biophysical origin remains unclear. Among the …

Acute cholestasis-induced renal failure: Effects of antioxidants and ligands for the thromboxane
A 2 receptor. Background Acute biliary obstruction is associated with the development of …

Partial portal vein ligation (PPVL) leads to the development of a hyperdynamic circulation. It
is associated with elevated levels of tumor necrosis factor (TNF-α) and nitric oxide (NO) …