Boosted protease inhibitor regimens combine ritonavir with a second, ‘boosted’ protease
inhibitor to enhance patient exposure to the latter agent, thereby preventing or overcoming …

Background In acquired thrombotic thrombocytopenic purpura (TTP), an immune-mediated
deficiency of the von Willebrand factor–cleaving protease ADAMTS13 allows unrestrained …

BACKGROUND: Approximately 45% of patients with chronic urticaria have an IgG autoantibody
directed to the α-subunit of the high-affinity IgE receptor (chronic autoimmune urticaria, …

Postpneumonectomy pulmonary edema has become a worldwide problem. Study of data
available from some of these patients implicates excessive perioperative volumes of …

By adjustment of the electronic properties of the ancilliary ligands, high selectivity can be
achieved for either [4 + 2] or [4 + 3] cycloaddition reactions of allene-dienes catalyzed by gold(I)…

… Kianifard, and RK Zeldin are employed by Novartis. H. Nelson has consultant arrangements
with Genentech/Novartis, Abbott Laboratories, MediciNova, AstraZeneca, Amgen, …

Background Preliminary studies have suggested the efficacy of sublingual tablets of house
dust mite (HDM) extracts in adults with allergic rhinitis. Objectives We sought to assess the …

Eosinophilia is an established marker of asthma-related inflammation. We assessed the effect
of omalizumab on peripheral blood eosinophil counts using a pooled analysis of data from …

BACKGROUND: Previous trials have demonstrated the efficacy, safety, and optimal dosage
of the 5-grass pollen sublingual tablet for adults and children with grass pollen–induced …

… De Winter 6 , RK Zeldin 6 … RK Zeldin designed research, analyzed and interpreted data,
and wrote the manuscript. … Goel R., King KE, Takemoto CM, Ness PM, Tobian AA …