[HTML][HTML] Marrow stromal cells for cellular cardiomyoplasty: feasibility and potential clinical advantages

…, E Chedrawy, N Eliopoulos, RCJ Chiu - The Journal of thoracic …, 2000 - Elsevier
Objectives: Marrow stromal cells are mesenchymal stem cells able to differentiate into
cardiomyocytes in vitro. We tested the hypothesis that marrow stromal cells, when implanted into …

Cellular cardiomyoplasty: myocardial regeneration with satellite cell implantation

RCJ Chiu, A Zibaitis, RL Kao - The Annals of thoracic surgery, 1995 - Elsevier
BACKGROUND.: Damaged skeletal muscle is able to regenerate because of the presence
of satellite cells, which are undifferentiated myoblasts. In contrast, destruction of cardiac …

Xenotransplant cardiac chimera: immune tolerance of adult stem cells

…, JQ Kuang, B Bittira, A Al-Khaldi, RCJ Chiu - The Annals of thoracic …, 2002 - Elsevier
Background. Bone marrow stromal cells have been shown to engraft into xenogeneic fetal
recipients. In view of the potential clinical utility as an alternative source for cellular and gene …

[HTML][HTML] The coronary delivery of marrow stromal cells for myocardial regeneration: pathophysiologic and therapeutic implications

…, D Shum-Tim, E Chedrawy, RCJ Chiu - The Journal of thoracic and …, 2001 - Elsevier
Objectives: Bone marrow stromal cells contain “adult stem cells.” We tested the hypothesis
that coronary-infused bone marrow stromal cells may populate the infarcted heart and …

Cell transplantation for myocardial repair: an experimental approach

…, M El-Alfy, RL Kao, RCJ Chiu - Cell …, 1992 - journals.sagepub.com
Myocardium lacks the ability to regenerate following injury. This is in contrast to skeletal
muscle (SKM), in which capacity for tissue repair is attributed to the presence of satellite cells. It …

[HTML][HTML] Myocardial tissue engineering with autologous myoblast implantation

…, MP Pelletier, D Shum-Tim, C Li, RCJ Chiu - The Journal of Thoracic …, 1998 - Elsevier
… I want to congratulate the group of Dr Chiu for this continued work in cellular cardiomyoplasty.
The European Union selected our group at Broussais Hospital in Paris to develop a …

[HTML][HTML] Transcoronary implantation of bone marrow stromal cells ameliorates cardiac function after myocardial infarction

T Saito, JQ Kuang, CCH Lin, RCJ Chiu - The Journal of Thoracic and …, 2003 - Elsevier
OBJECTIVES: Bone marrow stromal cells are capable of differentiating into cardiomyogenic
cells. We tested the hypothesis that transcoronary implantation of bone marrow stromal cells …

In vitro preprogramming of marrow stromal cells for myocardial regeneration

…, JQ Kuang, A Al-Khaldi, D Shum-Tim, RCJ Chiu - The Annals of thoracic …, 2002 - Elsevier
Background. We have previously reported that marrow stromal stem cells (MSCs), when
implanted into myocardium, can undergo milieu-dependent differentiation to express …

Angiogenesis and growth factor expression in a model of transmyocardial revascularization

…, J Dorfman, CM Li, A Philip, RCJ Chiu - The Annals of thoracic …, 1998 - Elsevier
… This is an outstanding example of basic research at the resident level and is a real tribute
to a fine thoracic surgery research laboratory, which has been directed by Dr Ray Chiu for a …

Bone-marrow stem cells as a source for cell therapy

RCJ Chiu - Heart failure reviews, 2003 - Springer
… MacDonald D, Saito T, Shum-Tim D, Bernier PL, Chiu RCJ. Early bone marrow stromal cell
xenotransplantation following myocardial infarction is associated with better left ventricular …