The present work is focused on the formulation of core–shell nanoparticles via the layer-by-layer
(LbL) self-assembly technique for delivery of biomacromolecules such as bone growth …

Recombinant human bone morphogenetic proteins (rhBMPs) have been extensively
investigated for developing therapeutic strategies aimed at the restoration and treatment of …

Localized and release-controlled delivery systems for the sustained expression of the
biologic potency of rhBMPs are essential. A substantial number of biomaterials have been …

Bone morphogenetic proteins (BMPs) are increasingly being used clinically to enhance
fracture repair and healing of non-unions. However, the potential efficacy of supraphysiological …

Forty-four consecutive cases of subacute osteomyelitis admitted at our institution over a 12-year
period were retrospectively reviewed to assess the effectiveness of conservative versus …

: Distraction osteogenesis is a form of in vivo tissue engineering in which the gradual separation
of cut bone edges results in the generation of new bone. In this study, the temporal and …

… Fifteen BMPs have been characterized and cloned so far, and all of them, except BMP~1,
which is a procoilagen C-protease, are members of the TGF—B superfarnily and share common …

FGF18 is a novel growth factor first reported in 1998. Current evidence suggests that FGF18
may play a prominent role in chondrogenesis and osteogenesis during skeletal …

We reviewed retrospectively 22 patients (23 limb segments) with fibular hemimelia treated
by amputation or limb lengthening to evaluate these methods of treatment. There were 12 …

The distraction osteogenesis (DO) technique has been used worldwide to treat many complex
orthopedic and craniofacial conditions. One limitation of this technique is the long time of …