Critically ill patients with 2009 influenza A (H1N1) infection in Canada
Context Between March and July 2009, the largest number of confirmed cases of 2009
influenza A(H1N1) infection occurred in North America. Objective To describe characteristics, …
influenza A(H1N1) infection occurred in North America. Objective To describe characteristics, …
A minimal common outcome measure set for COVID-19 clinical research
…, X Feng, T Fletcher, N Foster, R Fowler… - The lancet infectious …, 2020 - thelancet.com
Clinical research is necessary for an effective response to an emerging infectious disease
outbreak. However, research efforts are often hastily organised and done using various …
outbreak. However, research efforts are often hastily organised and done using various …
Critically ill patients with 2009 influenza A (H1N1) in Mexico
…, M Hernández, TE Stewart, RA Fowler - Jama, 2009 - jamanetwork.com
Context In March 2009, novel 2009 influenza A(H1N1) was first reported in the southwestern
United States and Mexico. The population and health care system in Mexico City …
United States and Mexico. The population and health care system in Mexico City …
Association between administration of IL-6 antagonists and mortality among patients hospitalized for COVID-19: a meta-analysis
Importance Clinical trials assessing the efficacy of IL-6 antagonists in patients hospitalized
for COVID-19 have variously reported benefit, no effect, and harm. Objective To estimate the …
for COVID-19 have variously reported benefit, no effect, and harm. Objective To estimate the …
Eligibility criteria of randomized controlled trials published in high-impact general medical journals: a systematic sampling review
HGC Van Spall, A Toren, A Kiss, RA Fowler - Jama, 2007 - jamanetwork.com
ContextSelective eligibility criteria of randomized controlled trials (RCTs) are vital to trial
feasibility and internal validity. However, the exclusion of certain patient populations may lead to …
feasibility and internal validity. However, the exclusion of certain patient populations may lead to …
What is an intensive care unit? A report of the task force of the World Federation of Societies of Intensive and Critical Care Medicine
…, B Connolly, JV Diaz, T Dorman, RA Fowler… - Journal of critical …, 2017 - Elsevier
Since their widespread introduction more than half a century ago, intensive care units (ICUs)
have become an integral part of the health care system. Although most ICUs are found in …
have become an integral part of the health care system. Although most ICUs are found in …
Comprehensive evidence-based clinical practice guidelines for ventilator-associated pneumonia: prevention
J Muscedere, P Dodek, S Keenan, R Fowler… - Journal of critical …, 2008 - Elsevier
BACKGROUND: Ventilator-associated pneumonia (VAP) is an important cause of morbidity
and mortality in ventilated critically ill patients. PURPOSE: To develop evidence-based …
and mortality in ventilated critically ill patients. PURPOSE: To develop evidence-based …
Remdesivir for the treatment of patients in hospital with COVID-19 in Canada: a randomized controlled trial
…, S English, G Farjou, E Fera, P Fontela, R Fowler… - Cmaj, 2022 - Can Med Assoc
Background: The role of remdesivir in the treatment of patients in hospital with COVID-19
remains ill defined in a global context. The World Health Organization Solidarity randomized …
remains ill defined in a global context. The World Health Organization Solidarity randomized …
How the COVID-19 pandemic will change the future of critical care
Coronavirus disease 19 (COVID-19) has posed unprecedented healthcare system challenges,
some of which will lead to transformative change. It is obvious to healthcare workers and …
some of which will lead to transformative change. It is obvious to healthcare workers and …
[HTML][HTML] Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention
…, MA Pfeffer, J Wittes, R Fowler… - … England Journal of …, 2005 - Mass Medical Soc
Background Selective cyclooxygenase-2 (COX-2) inhibitors have come under scrutiny
because of reports suggesting an increased cardiovascular risk associated with their use. …
because of reports suggesting an increased cardiovascular risk associated with their use. …