[HTML][HTML] Guidelines for the nomenclature of the human heat shock proteins
The expanding number of members in the various human heat shock protein (HSP) families
and the inconsistencies in their nomenclature have often led to confusion. Here, we propose …
and the inconsistencies in their nomenclature have often led to confusion. Here, we propose …
Hepatocytes corrected by gene therapy are selected in vivo in a murine model of hereditary tyrosinaemia type I
Current strategies for hepatic gene therapy are either quantitatively inefficient or suffer from
lack of permanent gene expression. We have utilized an animal model of hereditary …
lack of permanent gene expression. We have utilized an animal model of hereditary …
Synthesis and degradation of heat shock proteins during development and decay of thermotolerance
…, D Bernier, P Chrétien, LM Nicole, RM Tanguay… - Cancer research, 1982 - AACR
Morris hepatoma 7777 cells, heat conditioned at 43 for 0.5 hr, become gradually thermoresistant
during an incubation at 37 as judged by their ability to form colonies following a second …
during an incubation at 37 as judged by their ability to form colonies following a second …
Sulfidation of silver nanoparticles: natural antidote to their toxicity
Nanomaterials are highly dynamic in biological and environmental media. A critical need for
advancing environmental health and safety research for nanomaterials is to identify …
advancing environmental health and safety research for nanomaterials is to identify …
In vivo evaluation of carbon fullerene toxicity using embryonic zebrafish
There is a pressing need to develop rapid whole animal-based testing assays to assess the
potential toxicity of engineered nano-materials. To meet this challenge, the embryonic …
potential toxicity of engineered nano-materials. To meet this challenge, the embryonic …
Multidimensional In Vivo Hazard Assessment Using Zebrafish
…, MC Geier, HD Truong, RL Tanguay - Toxicological …, 2014 - academic.oup.com
There are tens of thousands of man-made chemicals in the environment; the inherent safety
of most of these chemicals is not known. Relevant biological platforms and new …
of most of these chemicals is not known. Relevant biological platforms and new …
Toxicity, uptake kinetics and behavior assessment in zebrafish embryos following exposure to perfluorooctanesulphonicacid (PFOS)
…, L Wang, X Ye, C Bai, MT Simonich, RL Tanguay… - Aquatic toxicology, 2010 - Elsevier
Perfluorooctanesulphonicacid (PFOS), a persistent organic contaminant, has been widely
detected in the environment, wildlife and humans, but few studies have assessed its effect on …
detected in the environment, wildlife and humans, but few studies have assessed its effect on …
[HTML][HTML] Translation initiation factors eIF-iso4G and eIF-4B interact with the poly (A)-binding protein and increase its RNA binding activity
H Le, RL Tanguay, ML Balasta, CC Wei… - Journal of Biological …, 1997 - ASBMB
The 5′-cap and the poly(A) tail act synergistically to increase the translational efficiency of
eukaryotic mRNAs, which suggests that these two mRNA elements communicate during …
eukaryotic mRNAs, which suggests that these two mRNA elements communicate during …
Translational efficiency is regulated by the length of the 3′ untranslated region
RL Tanguay, DR Gallie - Molecular and cellular biology, 1996 - Taylor & Francis
All polyadenylated mRNAs contain sequence of variable length between the coding region
and the poly(A) tail. Little has been done to establish what role the length of the 3′ …
and the poly(A) tail. Little has been done to establish what role the length of the 3′ …
Advanced morphological—behavioral test platform reveals neurodevelopmental defects in embryonic zebrafish exposed to comprehensive suite of halogenated and …
…, GD Gonnerman, RL Tanguay - Toxicological …, 2015 - academic.oup.com
The increased use of flammable plastics and electronic devices along with stricter fire safety
standards has led to the heavy use of flame retardant chemicals in many consumer, …
standards has led to the heavy use of flame retardant chemicals in many consumer, …