Emerging trends in the etiology, prevention, and treatment of gastrointestinal anastomotic leakage

SA Chadi, A Fingerhut, M Berho, SR DeMeester… - Journal of …, 2016 - Elsevier
… ALs create a substantial strain on both the patient’s quality of life and quality of the doctor–…
In an attempt to identify an AL prior to the onset of systemic changes in the patient’s status, …

Local resection compared with radical resection in the treatment of T1N0M0 rectal adenocarcinoma: a systematic review and meta-analysis

B Kidane, SA Chadi, S Kanters… - Diseases of the Colon …, 2015 - journals.lww.com
BACKGROUND: Local resection for early rectal cancer is thought to be less invasive but
oncologically inferior to radical resection. OBJECTIVE: The aim of this study was to compare …

Current evidence for minimally invasive surgery during the COVID-19 pandemic and risk mitigation strategies: a narrative review

SA Chadi, K Guidolin, A Caycedo-Marulanda… - Annals of …, 2020 - journals.lww.com
Objective: Our objective was to review the literature surrounding the risks of viral transmission
during laparoscopic surgery and propose mitigation measures to address these risks. …

Fibroblast growth factor 21 reduces the severity of cerulein-induced pancreatitis in mice

CL Johnson, JY Weston, SA Chadi, EN Fazio, MW Huff… - Gastroenterology, 2009 - Elsevier
BACKGROUND & AIMS: Fibroblast growth factor 21 (FGF21) acts as a hormonal regulator
during fasting and is involved in lipid metabolism. Fgf21 gene expression is regulated by …

Butyrate mediates anti-inflammatory effects of Faecalibacterium prausnitzii in intestinal epithelial cells through Dact3

M Lenoir, R Martín, E Torres-Maravilla, S Chadi… - Gut …, 2020 - Taylor & Francis
… For example, gut microbiota analysis of Crohn’s disease (a type of IBD) patients revealed …
prausnitzii’s anti-inflammatory effects within the host Citation4 , we still do not understand …

Factors affecting local regrowth after watch and wait for patients with a clinical complete response following chemoradiotherapy in rectal cancer (InterCoRe consortium …

SA Chadi, L Malcomson, J Ensor, RD Riley… - The lancet …, 2018 - thelancet.com
Background In patients with rectal cancer who achieve clinical complete response after
neoadjuvant chemoradiotherapy, watch and wait is a novel management strategy with potential …

Association between adjuvant chemotherapy and overall survival in patients with rectal cancer and pathological complete response after neoadjuvant chemotherapy …

…, SD Wexner, FA Quereshy, NN Baxter, SA Chadi - JAMA …, 2018 - jamanetwork.com
Importance Although American guidelines recommend use of adjuvant chemotherapy in
patients with locally advanced rectal cancer, individuals who achieve a pathological complete …

[HTML][HTML] Gut barrier-microbiota imbalances in early life lead to higher sensitivity to inflammation in a murine model of C-section delivery

…, Y Ramayo-Caldas, J Estellé, K Tambosco, S Chadi… - Microbiome, 2023 - Springer
Background Most interactions between the host and its microbiota occur at the gut barrier,
and primary colonizers are essential in the gut barrier maturation in the early life. The mother–…

[HTML][HTML] Human CD4+ CD8α+ Tregs induced by Faecalibacterium prausnitzii protect against intestinal inflammation

…, M Straube, C Galbert, L Brot, IA Salgueiro, S Chadi… - JCI insight, 2022 - ncbi.nlm.nih.gov
… prausnitzii in fecal microbiota in healthy individuals and patients with ileal Crohn’s disease.
… with IBD and are positively correlated in patients with Crohn’s disease with ileal involvement. …

Operative strategies for perforated diverticulitis: a systematic review and meta-analysis

…, SD Wexner, FA Quereshy, SA Chadi… - Diseases of the Colon …, 2018 - journals.lww.com
… The results of the Cochrane Collaboration’s tool for assessing risk of bias in RCTs are
presented in Table 3. Lack of blinding was a limitation for all of the included trials. Patients and …