User profiles for S. Salama

Sofie Salama

Acting Professor of MCD Bio; Faculty Dir. of Diversity UCSC Genomics Inst.
Verified email at ucsc.edu
Cited by 26277

MOG antibody disease: a review of MOG antibody seropositive neuromyelitis optica spectrum disorder

…, A Simpson, K Fritsche, S Salama, S Pardo… - Multiple sclerosis and …, 2018 - Elsevier
MOG antibody disease is an autoimmune disease of the central nervous system associated
with a serological antibody against MOG, myelin oligodendrocyte glycoprotein. MOG is a …

[HTML][HTML] Association of CNS demyelination and COVID-19 infection: an updated systematic review

II Ismail, S Salama - Journal of Neurology, 2022 - Springer
Background Since the declaration of COVID-19 pandemic, several case reports of demyelination
of both peripheral and central nervous systems have been published. The association …

[HTML][HTML] The somatic genomic landscape of glioblastoma

…, B Campos, H Noushmehr, SR Salama, S Zheng… - cell, 2013 - cell.com
We describe the landscape of somatic genomic alterations based on multidimensional and
comprehensive characterization of more than 500 glioblastoma tumors (GBMs). We identify …

[PDF][PDF] Molecular profiling reveals biologically discrete subsets and pathways of progression in diffuse glioma

…, FP Barthel, TM Malta, TS Sabedot, SR Salama… - Cell, 2016 - cell.com
Therapy development for adult diffuse glioma is hindered by incomplete knowledge of somatic
glioma driving alterations and suboptimal disease classification. We defined the complete …

An RNA gene expressed during cortical development evolved rapidly in humans

…, SR Salama, N Lambert, MA Lambot, S Coppens… - Nature, 2006 - nature.com
The developmental and evolutionary mechanisms behind the emergence of human-specific
brain features remain largely unknown. However, the recent ability to compare our genome …

A systematic review of cases of CNS demyelination following COVID-19 vaccination

II Ismail, S Salama - Journal of neuroimmunology, 2022 - Elsevier
Background Since the emergency use approval of different types of COVID-19 vaccines,
several safety concerns have been raised regarding its early and delayed impact on the …

Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E

DC Fingar, S Salama, C Tsou, ED Harlow… - Genes & …, 2002 - genesdev.cshlp.org
… To determine whether rapamycin reduces cell size during other phases of the cell cycle, we
examined the mean FSC-H of S-phase and G 2 /M-phase cells. Rapamycin decreased cell …

Complete genomic and epigenetic maps of human centromeres

…, S Brooks, A Young, S Nurk, S Koren, SR Salama… - Science, 2022 - science.org
Existing human genome assemblies have almost entirely excluded repetitive sequences
within and near centromeres, limiting our understanding of their organization, evolution, and …

[PDF][PDF] Key parameters of tumor epitope immunogenicity revealed through a consortium approach improve neoantigen prediction

…, S Qiu, S Sarkizova, S Salama, S Liu, S Wu, S Sridhar… - Cell, 2020 - cell.com
Many approaches to identify therapeutically relevant neoantigens couple tumor sequencing
with bioinformatic algorithms and inferred rules of tumor epitope immunogenicity. However, …

[HTML][HTML] Nanopore sequencing and the Shasta toolkit enable efficient de novo assembly of eleven human genomes

…, J Monlong, E Garrison, EE Eichler, S Salama… - Nature …, 2020 - nature.com
… Finally, we used QUAST to calculate disagreements between the T2T Consortium’s
chromosome X assembly, a highly curated, validated assembly 32 and the subset of each CHM13 …