Aims/Objectives/Background: A significant number of people who experience chronic pain
also complain of depression and sleep problems. The comorbidities and bidirectional …

BACKGROUND: Research has found that chronic pain disrupts attention and that this
disruption can lead to significant functional impairment and decreased quality of life. We …

Accumulating evidence points to significant cognitive disruption in individuals with Fibromyalgia
Syndrome (FMS). This study was carried out in order to examine specific cognitive …

Conclusion No difference was observed between the epidural and control groups in disease-free
survival at a median follow-up time of 4.5 years. There is a need for large randomized …

Background: Buprenorphine is a mixed-activity, partial μ-opioid agonist. Its lipid solubility
makes it well suited for transdermal administration. Objective: This study assessed the efficacy …

Chronic masticatory myalgia (CMM) can be defined as constant pain in the masticatory
muscles for more than 6 months and is influenced by the central nervous system. The …

OBJECTIVE: The present randomized, double-blinded, crossover study compared the
efficacy and safety of a seven-day buprenorphine transdermal system (BTDS) and placebo in …

Purpose Preoperative investigations are frequently ordered according to care maps or protocols.
We hypothesized that selective ordering of investigations by anesthesiology staff would …

Background Total joint arthroplasty (TJA) patients often receive allogeneic blood transfusion.
The use of regional anesthesia (RA) is thought to protect against the need for blood …

Study Design. Historical cohort study. Objective. We investigated the prescription of opioids
in injured Canadian workers to determine recent trends in use and the association between …