Relation between kidney function, proteinuria, and adverse outcomes

…, BJ Manns, A Lloyd, MT James, S Klarenbach… - Jama, 2010 - jamanetwork.com
Context The current staging system for chronic kidney disease is based primarily on estimated
glomerular filtration rate (eGFR) with lower eGFR associated with higher risk of adverse …

Risk of coronary events in people with chronic kidney disease compared with those with diabetes: a population-level cohort study

M Tonelli, P Muntner, A Lloyd, BJ Manns, S Klarenbach… - The Lancet, 2012 - thelancet.com
Background Diabetes is regarded as a coronary heart disease risk equivalent—ie, people
with the disorder have a risk of coronary events similar to those with previous myocardial …

[HTML][HTML] Guidelines for the management of chronic kidney disease

…, B Manns, C White, F Madore, L Moist, S Klarenbach… - Cmaj, 2008 - Can Med Assoc
New guidelines for the management of chronic kidney disease have been developed by the
Canadian Society of Nephrology (Appendix 1 contains the fulltext guidelines; available at …

Effect of frequent nocturnal hemodialysis vs conventional hemodialysis on left ventricular mass and quality of life: a randomized controlled trial

…, M Walsh, SW Klarenbach, G Mortis, N Scott-Douglas… - Jama, 2007 - jamanetwork.com
ContextMorbidity and mortality rates in hemodialysis patients remain excessive. Alterations
in the delivery of dialysis may lead to improved patient outcomes.ObjectiveTo compare the …

[HTML][HTML] A population-based cohort study defines prognoses in severe chronic kidney disease

M Tonelli, N Wiebe, MT James, SW Klarenbach… - Kidney International, 2018 - Elsevier
In older people with chronic kidney disease (CKD) and comorbidities, the risk of death or
disability may overshadow the risk of kidney failure. To help refine this we did a retrospective …

Impact of anemia on hospitalization and mortality in older adults

…, BJ Manns, J Zhang, M Tonelli, S Klarenbach… - Blood, 2006 - ashpublications.org
Although anemia is common in older adults, its prognostic significance is uncertain. A total
of 17 030 community-dwelling subjects 66 years and older were identified between July 1 …

Cause of death in patients with reduced kidney function

…, B Hemmelgarn, B Manns, S Klarenbach… - Journal of the …, 2015 - journals.lww.com
Abstract Information on common causes of death in people with CKD is limited. We hypothesized
that, as eGFR declines, cardiovascular mortality and mortality from infection account for …

Renal replacement therapy in patients with acute renal failure: a systematic review

N Pannu, S Klarenbach, N Wiebe, B Manns, M Tonelli… - JaMa, 2008 - jamanetwork.com
Context Acute renal failure requiring dialytic support is associated with a high risk of mortality
and substantial morbidity. Objectives To summarize current evidence guiding provision of …

Associations between acute kidney injury and cardiovascular and renal outcomes after coronary angiography

…, P Faris, N Pannu, BJ Manns, SW Klarenbach… - Circulation, 2011 - Am Heart Assoc
Background— Acute kidney injury (AKI) is associated with early mortality after percutaneous
coronary revascularization procedures, but its prognostic relevance to long-term clinical …

Glomerular filtration rate, proteinuria, and the incidence and consequences of acute kidney injury: a cohort study

…, N Wiebe, N Pannu, BJ Manns, SW Klarenbach… - The Lancet, 2010 - thelancet.com
Background Low values of estimated glomerular filtration rate (eGFR) predispose to acute
kidney injury, and proteinuria is a marker of kidney disease. We aimed to investigate how …