User profiles for Sean P. Cleary
 | Sean ClearyDepartment of Surgery, Mayo Clinic Verified email at mayo.edu Cited by 13896 |
A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns
Pancreatic cancer, a highly aggressive tumour type with uniformly poor prognosis,
exemplifies the classically held view of stepwise cancer development 1 . The current model of …
exemplifies the classically held view of stepwise cancer development 1 . The current model of …
Recurrence after liver resection for hepatocellular carcinoma: risk factors, treatment, and outcomes
BACKGROUND: Tumor recurrence remains the major cause of death after curative resection
for hepatocellular carcinoma (HCC). The purpose of this study was to identify risk factors for …
for hepatocellular carcinoma (HCC). The purpose of this study was to identify risk factors for …
Prognostic factors in resected pancreatic adenocarcinoma: analysis of actual 5-year survivors
SP Cleary, R Gryfe, M Guindi, P Greig, L Smith… - Journal of the American …, 2004 - Elsevier
BACKGROUND: Pancreatic cancer is a rapidly fatal disease with very few 5-year survivors
even after aggressive surgical treatment. Our objective was to determine the actual 5-year …
even after aggressive surgical treatment. Our objective was to determine the actual 5-year …
[HTML][HTML] Factors predicting response, perioperative outcomes, and survival following total neoadjuvant therapy for borderline/locally advanced pancreatic cancer
…, DM Nagorney, RL Smoot, SP Cleary… - Annals of …, 2021 - journals.lww.com
Objective: To identify predictive factors associated with operative morbidity, mortality, and
survival outcomes in patients with borderline resectable (BR) or locally advanced (LA) …
survival outcomes in patients with borderline resectable (BR) or locally advanced (LA) …
[PDF][PDF] Identification of driver genes in hepatocellular carcinoma by exome sequencing
Genetic alterations in specific driver genes lead to disruption of cellular pathways and are
critical events in the instigation and progression of hepatocellular carcinoma (HCC). As a …
critical events in the instigation and progression of hepatocellular carcinoma (HCC). As a …
[PDF][PDF] The extended Toronto criteria for liver transplantation in patients with hepatocellular carcinoma: A prospective validation study
The selection of liver transplant candidates with hepatocellular carcinoma (HCC) relies
mostly on tumor size and number. Instead of relying on these factors, we used poor tumor …
mostly on tumor size and number. Instead of relying on these factors, we used poor tumor …
The Toronto General Hospital Transitional Pain Service: development and implementation of a multidisciplinary program to prevent chronic postsurgical pain
…, V Rao, D Grant, G Roche-Nagle, SP Cleary… - Journal of pain …, 2015 - Taylor & Francis
Chronic postsurgical pain (CPSP), an often unanticipated result of necessary and even life-saving
procedures, develops in 5–10% of patients one-year after major surgery. Substantial …
procedures, develops in 5–10% of patients one-year after major surgery. Substantial …
Association between biallelic and monoallelic germline MYH gene mutations and colorectal cancer risk
ME Croitoru, SP Cleary, N Di Nicola… - Journal of the …, 2004 - academic.oup.com
The MutY human homologue (MYH) gene encodes a member of the base excision repair
pathway that is involved in repairing oxidative damage to DNA. Two germline MYH gene …
pathway that is involved in repairing oxidative damage to DNA. Two germline MYH gene …
Common variation at 2p13. 3, 3q29, 7p13 and 17q25. 1 associated with susceptibility to pancreatic cancer
…, GM Cavestro, KG Chaffee, SJ Chanock, SP Cleary… - Nature …, 2015 - nature.com
Pancreatic cancer is the fourth leading cause of cancer death in the developed world 1 . Both
inherited high-penetrance mutations in BRCA2 (ref. 2 ), ATM 3 , PALB2 (ref. 4 ), BRCA1 (ref…
inherited high-penetrance mutations in BRCA2 (ref. 2 ), ATM 3 , PALB2 (ref. 4 ), BRCA1 (ref…
Germline MutY human homologue mutations and colorectal cancer: a multisite case-control study
BACKGROUND & AIMS: The MutY human homologue (MYH) gene is a member of the base-excision
repair pathway involved in the repair of oxidative DNA damage. The objective of …
repair pathway involved in the repair of oxidative DNA damage. The objective of …