Background: Pain is one of the most common and distressing symptoms reported by adolescents
with cancer. Despite advancements in pain assessment and management research, …

Enchondromas are common benign cartilage tumors of bone. They can occur as solitary
lesions or as multiple lesions in enchondromatosis (Ollier and Maffucci diseases). Clinical …

The study of nuclear mechanical properties can provide insights into nuclear dynamics and
its role in cellular mechanotransduction. While several methods have been developed to …

Chondrosarcoma is a malignant cartilage tumor that may arise from benign precursor lesions,
such as enchondromas. Some cases of multiple enchondromas are caused by a mutation …

BACKGROUND: As Ewing sarcoma (EWS) can affect children and adults, these patients
can be treated at either a pediatric or an adult institution. This study investigated whether …

The capability to directly interrogate intracellular structures inside a single cell for measurement
and manipulation is important for understanding subcellular and suborganelle activities, …

The vertebrate limb bud arises from lateral plate mesoderm and its overlying ectoderm.
Despite progress regarding the genetic requirements for limb development, morphogenetic …

The physical forces that drive morphogenesis are not well characterized in vivo, especially
among vertebrates. In the early limb bud, dorsal and ventral ectoderm converge to form the …

Limb skeletal pattern relies heavily on graded Sonic hedgehog (Shh) signaling. As a morphogen
and growth cue, Shh regulates identities of posterior limb elements, including the ulna/…

We evaluated the construct validity (including responsiveness), reliability, and feasibility of
the Pain Squad multidimensional smartphone-based pain assessment application (app) in …