User profiles for Stéphanie Jean

Stéphanie Jean-Daubias

LIRIS - Université Lyon 1
Verified email at liris.univ-lyon1.fr
Cited by 923

Application de recommandations ergonomiques: spécificités des EIAO dédiés à l'évaluation

S Jean - 2000 - hal.science
Les recherches en EIAO (environnements interactifs d'apprentissage avec ordinateur) font
de plus en plus souvent appel à des problématiques d'IHM. Les résultats des recherches en …

PÉPITE: un système d'assistance au diagnostic de compétences

S Jean-Daubias - 2000 - theses.hal.science
Notre travail de recherche a pour objectif de modéliser les connaissances des élèves en
algèbre élémentaire en construisant leur profil cognitif pour la transition entre la troisième et la …

[HTML][HTML] Aggregation of alpha-synuclein disrupts mitochondrial metabolism and induce mitophagy via cardiolipin externalization

…, R Martín-Jiménez, M Khan, R Sheta, S Jean… - Cell Death & …, 2023 - nature.com
Accumulation of α-synuclein aggregates in the substantia nigra pars compacta is central in
the pathophysiology of Parkinson’s disease, leading to the degeneration of dopaminergic …

[PDF][PDF] A functional genomic approach identifies FAL1 as an oncogenic long noncoding RNA that associates with BMI1 and represses p21 expression in cancer

…, Y Zhang, L Yang, X Zhong, LP Wang, S Jean… - Cancer cell, 2014 - cell.com
In a genome-wide survey on somatic copy-number alterations (SCNAs) of long noncoding
RNA (lncRNA) in 2,394 tumor specimens from 12 cancer types, we found that about 21.8% of …

[HTML][HTML] Intramitochondrial Src kinase links mitochondrial dysfunctions and aggressiveness of breast cancer cells

MA Djeungoue-Petga, O Lurette, S Jean… - Cell death & …, 2019 - nature.com
High levels and activity of Src kinase are common among breast cancer subtypes, and several
inhibitors of the kinase are currently tested in clinical trials. Alterations in mitochondrial …

Gleevec inhibits β-amyloid production but not Notch cleavage

…, F Dou, D Cai, D Veach, S Jean… - Proceedings of the …, 2003 - National Acad Sciences
Amyloid-β (Aβ) peptides, consisting mainly of 40 and 42 aa (Aβ40 and Aβ42, respectively),
are metabolites of the amyloid precursor protein and are believed to be major pathological …

[HTML][HTML] Pax-5 is a potent regulator of E-cadherin and breast cancer malignant processes

S Benzina, AP Beauregard, R Guerrette, S Jean… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Pax-5, an essential transcription factor for B lymphocyte development, has been linked with
the development and progression of lymphoid cancers and carcinoma. In contrast to B-cell …

The endocannabinoid metabolite prostaglandin E2 (PGE2)-glycerol inhibits human neutrophil functions: involvement of its hydrolysis into PGE2 and EP receptors

C Turcotte, S Zarini, S Jean, C Martin… - The Journal of …, 2017 - journals.aai.org
The endocannabinoids 2-arachidonoyl-glycerol and N-arachidonoyl-ethanolamine mediate
an array of pro-and anti-inflammatory effects. These effects are related, in part, to their …

N6-Methylation of Adenosine of FZD10 mRNA Contributes to PARP Inhibitor Resistance

…, S Wu, P Liu, AV Kossenkov, LC Showe, S Jean… - Cancer research, 2019 - AACR
These findings elucidate a novel regulatory mechanism of PARPi resistance in EOC by
showing that m 6 A modification of FZD10 mRNA contributes to PARPi resistance in BRCA-…

Adiponectin influences progesterone production from MA-10 Leydig cells in a dose-dependent manner

D Landry, A Paré, S Jean, LJ Martin - Endocrine, 2015 - Springer
Obesity in men is associated with lower testosterone levels, related to reduced sperm
concentration and the development of various diseases with aging. Hormones produced by the …