… , stated when referring to knockout mice: «I don't believe there is a single mouse that doesn’t
have a phenotype … … We just aren't asking the right questions.» [63]. The presence of …

The vertebrate spleen has important functions in immunity and haematopoiesis, many of
which have been well studied. In contrast, we know much less about the mechanisms …

The mechanisms by which physical forces regulate endothelial cells to determine the
complexities of vascular structure and function are enigmatic 1 , 2 , 3 , 4 , 5 . Studies of sensory …

… It has been stated that the scrutiny of professional boards and monitoring programs has, in
some cases, created fear that legal action will be taken against physicians and pharmacists re…

Mutations in a number of genes have been linked to inherited dilated cardiomyopathy (DCM).
However, such mutations account for only a small proportion of the clinical cases …

A method of measuring the acoustic flow resistance and reactance of porous materials is
described, and some illustrative experimental data are presented and discussed. For example, …

It has been suggested that metastasis‐initiating cells gain a foothold in bone by homing to a
metastastatic microenvironment (or “niche”). Whereas the precise nature of this niche …

… of groups of genes in T-cell acute lymphoblastic leukemias (T-ALLs) (1). In T-ALLs, three
classes of … A third class of gene product implicated in T-ALL is the HOX1l protein encoded by a …

The HOX11 homeobox gene was identified via the translocation t(10;14) in T cell leukaemia.
To determine the function of this gene in mice, null mutations were made using …

… cDNA preparation and subtraction were performed as described (Dear et al., 1991). A
total cDNA library from OM poly(A)+ RNA was constructed in XgtlO using a cDNA cloning kit …