User profiles for T. Derek Cooke

Theodore Derek Cooke

Adjunct Professor School Rehabilitation, Queens University , Kingston, ON, Canada
Verified email at cookes.ca
Cited by 20228

Identification of immunoglobulins and complement in rheumatoid articular collagenous tissues

TD Cooke, ER Hurd, HE Jasin… - … : Official Journal of the …, 1975 - Wiley Online Library
Ninety‐three patients with a variety of joint diseases were studied for evidence of immune
complexes in articular collagenous tissues. Frozen sections of freshly obtained biopsies of …

The pathogenesis of chronic inflammation in experimental antigen-induced arthritis: II. Preferential localization of antigen-antibody complexes to collagenous tissues

TD Cooke, ER Hurd, M Ziff, HE Jasin - The Journal of experimental …, 1972 - rupress.org
In an experimental arthritis induced by injection of bovine serum albumin or egg albumin into
the joints of previously immunized animals, it has been demonstrated that the major portion …

The pathogenesis of chronic inflammation in experimental antigen‐induced arthritis. I. The role of antigen on the local immune response

TD Cooke, HE Jasin - Arthritis & Rheumatism: Official Journal of …, 1972 - Wiley Online Library
Using the model described by Dumonde and Glynn in which a chronic synovitis is induced by
the intraarticular injection of antigen in previously immunized rabbits, marked chronic local …

Electron microscopic morphology of immunoglobulin aggregates and their interactions in rheumatoid articular collagenous tissues

O Ohno, TD Cooke - Arthritis & Rheumatism: Official Journal of …, 1978 - Wiley Online Library
Immunoelectron microscopy for IgG and IgA was combined with plain electron microscopy
and light microscopy to study a variety of articular collagenous tissues from 14 cases of …

Analysis of limb alignment in the pathogenesis of osteoarthritis: a comparison of Saudi Arabian and Canadian cases

DT Cooke, L Harrison, B Khan, A Scudamore… - Rheumatology …, 2002 - Springer
A study was made of alignment abnormalities and bone deformities in Saudis with
osteoarthritis (SOA). Data from standardized radiography of hips and knees were: hip-knee-ankle …

Varus and valgus alignment and incident and progressive knee osteoarthritis

…, CE Lewis, N Segal, J Torner, TDV Cooke… - Annals of the …, 2010 - ard.bmj.com
Objective Varus and valgus alignment increase medial and lateral tibiofemoral load. Alignment
was associated with tibiofemoral osteoarthritis progression in previous studies; an effect …

Frontal plane knee alignment: a call for standardized measurement

TDV Cooke, EA Sled… - Journal of …, 2007 - digitalcommons.cedarville.edu
Evaluations of knee alignment are useful in the diagnosis of arthritic conditions affecting the
knee joint, serving also as a guide for conservative management and surgical planning. …

Valgus malalignment is a risk factor for lateral knee osteoarthritis incidence and progression: findings from the Multicenter Osteoarthritis Study and the Osteoarthritis …

…, M Englund, L Sharma, TDV Cooke… - Arthritis & …, 2013 - Wiley Online Library
Objective To study the effect of valgus malalignment on knee osteoarthritis (OA) incidence
and progression. Methods We measured the mechanical axis from long limb radiographs from …

Tibial anatomy and functional axes

…, DW Siu, RA Scudamore, TDV Cooke - Journal of …, 1989 - Wiley Online Library
Articular geometry of the tibia has been studied in relation to the functional axis and extra‐articular
bone landmarks, using a Cartesian coordinate system. Thirty‐one cadaver limbs were …

The role of varus and valgus alignment in the initial development of knee cartilage damage by MRI: the MOST study

…, CE Lewis, N Segal, J Torner, TDV Cooke… - Annals of the …, 2013 - ard.bmj.com
Objective Varus and valgus alignment are associated with progression of knee osteoarthritis,
but their role in incident disease is less certain. Radiographic measures of incident knee …