We have previously shown that CEACAM1, a cell-adhesion molecule, acts as a tumor
suppressor in prostate carcinoma. Expression of CEACAM1 in prostate cancer cells suppresses …

CEACAM1 is a cell-cell adhesion molecule that mediates homophilic cell adhesion. In addition,
CEACAM1 was also shown to suppress the growth of prostate, breast, and colon tumors. …

We have previously shown that C-CAM1 cell adhesion molecule can suppress the growth of
prostate cancer cells in vivo. In this study, we determined the minimal domain of C-CAM1 …

… The number of T cells and macrophages in the aortic media of the aneurysm correlated …
T-cell receptor profiling indicated a similar clonal nature of the T cells in the aortic wall in a …

OBJECTIVE: The histopathologic abnormality underlying ascending aortic aneurysm and
dissection is medial degeneration, a lesion that is described as the noninflammatory loss of …

Background— A genetic predisposition for progressive enlargement of thoracic aortic
aneurysms leading to type A dissection (TAAD) is inherited in an autosomal-dominant manner in …

Objective: The aim of this study was to determine the sex representation among principal
investigators (PIs) in US cardiac surgery clinical trials. Summary Background Data: Being a …

Rationale: Mutations in several genes have been identified that are responsible for 25% of
families with familial thoracic aortic aneurysms and dissections. However, the causative gene …

Postoperative renal failure and insufficiency are important complications of operations that
require thoracic aortic cross-clamping. Successful application of pharmacologic methods to …

Background— The benefit of retrograde cerebral perfusion (RCP) with profound hypothermic
circulatory arrest has been subject to much debate. We examined our experience with …