Transfusion of plasma, platelets, and red blood cells in a 1: 1: 1 vs a 1: 1: 2 ratio and mortality in patients with severe trauma: the PROPPR randomized clinical trial

…, TC Fabian, K Inaba, JD Kerby, P Muskat, T O'Keeffe… - Jama, 2015 - jamanetwork.com
Importance Severely injured patients experiencing hemorrhagic shock often require massive
transfusion. Earlier transfusion with higher blood product ratios (plasma, platelets, and red …

Conjugative transfer of clostridial shuttle vectors from Escherichia coli to Clostridium difficile through circumvention of the restriction barrier

D Purdy, TAT O'Keeffe, M Elmore… - Molecular …, 2002 - Wiley Online Library
Progress towards understanding the molecular basis of virulence in Clostridium difficile has
been hindered by the lack of effective gene transfer systems. We have now, for the first time, …

Superiority of frailty over age in predicting outcomes among geriatric trauma patients: a prospective analysis

…, N Kulvatunyou, A Hashmi, DJ Green, T O'Keeffe… - JAMA …, 2014 - jamanetwork.com
… To analyze data, we used t test for parametric variables and Mann-Whitney test for
nonparametric variables. χ 2 Test was used to assess differences in proportions for categorical …

Every minute counts: time to delivery of initial massive transfusion cooler and its impact on mortality

DE Meyer, LE Vincent, EE Fox, T O'Keeffe… - … of Trauma and Acute …, 2017 - journals.lww.com
BACKGROUND American College of Surgeons Trauma Quality Improvement Best Practices
recommends initial massive transfusion (MT) cooler delivery within 15 minutes of protocol …

Evidence supporting routine polysomnography before bariatric surgery

T O'keeffe, EJ Patterson - Obesity surgery, 2004 - Springer
Background: Obstructive sleep apnea (OSA) is common in morbidly obese patients, with a
reported prevalence from 12 to 40%. Preoperative diagnosis of OSA is important for both …

A massive transfusion protocol to decrease blood component use and costs

T O'Keeffe, M Refaai, K Tchorz, JE Forestner… - Archives of …, 2008 - jamanetwork.com
… Critical revision of the manuscript for important intellectual content: OKeeffe, Tchorz, … Dr
O'Keeffe: First, the decision to activate the MTP is made by the trauma team in the trauma hall, …

Tranexamic acid during prehospital transport in patients at risk for hemorrhage after injury: a double-blind, placebo-controlled, randomized clinical trial

…, R Nirula, GA Vercruysse, T O'Keeffe… - JAMA …, 2021 - jamanetwork.com
Importance In-hospital administration of tranexamic acid after injury improves outcomes in
patients at risk for hemorrhage. Data demonstrating the benefit and safety of the pragmatic …

Emergency general surgery in the elderly: too old or too frail?

…, N Kulvatunyou, TO Jokar, T O'Keeffe… - … the American College of …, 2016 - Elsevier
Background Assessment of operative risk in geriatric patients undergoing emergency general
surgery (EGS) is challenging. Frailty is an established measure for risk assessment in …

Validating trauma-specific frailty index for geriatric trauma patients: a prospective analysis

…, B Zangbar, N Kulvatunyou, A Tang, T O'Keeffe… - … the American College of …, 2014 - Elsevier
Background The Frailty Index has been shown to predict discharge disposition in geriatric
patients. The aim of this study was to validate the modified 15-variable Trauma-Specific Frailty …

Magnetostatic surface‐wave propagation in finite samples

TW O'keeffe, RW Patterson - Journal of Applied Physics, 1978 - pubs.aip.org
The dispersion relation of magnetostatic surface waves propagating in a ferromagnetic film
of finite dimensions is derived. Specifically, a consideration of the finite width of the sample is …