The binding of a T cell to an APC results in T cell actin cytoskeletal rearrangement leading
to the formation of an immunological synapse. The APC cytoskeleton has been thought to …

Background: Recently, echinacea has regained popularity as one of the treatments chosen
most commonly by consumers with the expectation that it will reduce the severity and …

Background. Postsurgical adhesion formation can result in significant morbidity and, to a
lesser extent, death. The purpose of this experiment was to assess the ability of N,O-…

Maturation of dendritic cells (DC) is critical to their development into potent APCs. Upon
maturation, DC up-regulate the expression of MHC class II as well as costimulatory and …

BACKGROUND: Postoperative adhesions have proven to be intractable complications after
abdominal operations. This study assessed the efficacy of N, O - carboxymethyl chitosan (…

Macrophages are increasingly recognized as a potential therapeutic target in myocardial
fibrosis via interactions with fibroblasts. We have characterized macrophage depletion and …

Background. Adhesion formation after operation can result in major complications. We have
previously demonstrated that N,O-carboxymethyl chitosan (NOCC) is an effective inhibitor of …

Myocardial fibrosis is characterized by significant extracellular matrix (ECM) deposition. The
specific cellular mediators that contribute to the development of fibrosis are not well …

Public interest in Echinacea is growing rapidly. Unfortunately, there is little scientific evidence
to support claims of efficacy of this widely used botanical, and little information about …

Chronic rejection is the most common cause of late graft failure after solid organ transplantation.
A model of chronic rejection, the rat aortic allograft, has histologic features that parallel …