Background Hyaluronic acid (HA), lubricin, and phospholipid species (PLs) contribute
independently or together to the boundary lubrication of articular joints that is provided by synovial …

Objective The purposes of this study were 1) to quantify the proteoglycan 4 (PRG4) and
hyaluronan (HA) content in synovial fluid (SF) from normal donors and from patients with chronic …

Osteoarthritis (OA) is a leading cause of chronic joint pain in the older human population.
Diagnosis of OA at an earlier stage may enable the development of new treatments to one day …

Background Proteoglycan 4 (PRG4) and hyaluronan (HA) are key synovial fluid constituents
that contribute synergistically to cartilage boundary lubrication; however, the effects of their …

Objective To determine if three-dimensionally printed (3Dp) fracture models can improve
orthopedic trainee education. Design A prospective comparison study of orthopedic trainees …

… Joly MD a , Taryn Ludwig MD, PhD a , Saboura Mahdavi MSc b c , Hoa Khong MD, MPH d ,
Sophie Gh. Piroozfar MSc c d , Rajrishi Sharma MSc… Conflict of Interest Statement for Ludwig. …

The objective of this study was to determine changes in (1) proteoglycan 4 (PRG4) and
hyaluronan (HA) concentration, (2) HA molecular weight (MW) distribution, and (3) cartilage …

BACKGROUND: The contribution of proteoglycan 4 (PRG4) to synovial fluid and
hyaluronan (HA) solution rheology are poorly understood. The effects of PRG4 disulfide-bonded …

Objectives: The aim of this study is to report the impact of public health measures (PHM),
including their relaxation, on surgical orthopaedic trauma volumes. We hypothesize an initial …

Background: The Ames-International Spine Study Group (AMES) classification is used as a
tool for stratifying severity in adult cervical deformity (ACD). The AMES sagittal modifiers …