[HTML][HTML] Growth differentiation factor-15 deficiency augments inflammatory response and exacerbates septic heart and renal injury induced by lipopolysaccharide

…, N Loganathan, D Zhao, T Mele, Y Zhang, T Zwiep… - Scientific reports, 2017 - nature.com
Septic acute kidney injury (AKI) and myocardial dysfunction are leading causes of mortality
with no accepted method of therapy. In this study we demonstrate the role of growth …

[HTML][HTML] Clinical practice guideline: evidence, recommendations and algorithm for the preoperative optimization of anemia, hyperglycemia and smoking

JA Greenberg, TM Zwiep, J Sadek… - Canadian Journal of …, 2021 - ncbi.nlm.nih.gov
For most of the 20th century, the focus of research in surgery was improvements in intraoperative
technique, which led to major technical paradigm shifts exemplified by the evolution of …

Group practice impacts on patients, physicians and healthcare systems: a scoping review

T Zwiep, J Brehaut, F Balaa, DI McIsaac, S Rich… - BMJ open, 2021 - bmjopen.bmj.com
Objective To identify the advantages and disadvantages that group practices have on patients,
physicians and healthcare systems. Study design A scoping review was performed based …

Comparison of ligation of the intersphincteric fistula tract and BioLIFT for the treatment of transsphincteric anal fistula: a retrospective analysis

TM Zwiep, R Gilbert, RP Boushey… - Diseases of the Colon …, 2020 - journals.lww.com
BACKGROUND: Ligation of the intersphincteric fistula tract is a sphincter-preserving technique
for the treatment of anal fistulas. The BioLIFT modification involves the placement of a …

Acute gastric volvulus in a six-year-old: a case report and review of the literature

…, H Emmerton-Coughlin, S Mehrotra, T Zwiep… - The Journal of …, 2014 - Elsevier
Background First described in the pediatric population in 1899 by Oltmann, pediatric gastric
volvulus is a rare disease, but carries a high mortality rate. Due to vague signs and …

Comparison of BioLIFT versus LIFT for the treatment of trans-sphincteric anal fistula: a protocol for systematic review and meta-analysis

R Hu, R Gilbert, T Zwiep, H Moloo, L Williams… - BMJ open, 2023 - bmjopen.bmj.com
Introduction Identifying the optimal treatment for anal fistula has been challenging. Since
first reported in 2007, the ligation of the intersphincteric fistula tract (LIFT) procedure has …

[HTML][HTML] Prevention of allograft rejection in heart transplantation through concurrent gene silencing of TLR and Kinase signaling pathways

…, X Zhang, X Zheng, Z Lan, J Shi, J Jiang, T Zwiep… - Scientific Reports, 2016 - nature.com
Toll-like receptors (TLRs) act as initiators and conductors responsible for both innate and
adaptive immune responses in organ transplantation. The mammalian target of rapamycin (…

Impact of COVID‐19 Pandemic on Readmission Rates Following Colorectal Surgery: A Retrospective Cohort Study

…, K Vogt, M Brackstone, T Zwiep - World Journal of …, 2023 - Wiley Online Library
Background The COVID‐19 pandemic placed increased pressure to discharge patients early;
this could have resulted in rushed discharges requiring patients to return to hospital. The …

Outcomes of patients undergoing elective bowel resection before and after implementation of an anemia screening and treatment program

RWD Gilbert, T Zwiep, J Greenberg… - Diseases of the Colon …, 2022 - journals.lww.com
BACKGROUND: Patients with anemia undergoing elective colorectal cancer surgery are
known to have significantly higher rates of postoperative complications and worse outcomes. …

[HTML][HTML] Associations of preoperative anaemia with healthcare resource use and outcomes after colorectal surgery: a population-based cohort study

…, T Ramsay, K Thavorn, J Presseau, T Zwiep… - British Journal of …, 2024 - Elsevier
Background Preoperative anaemia is common in patient undergoing colorectal surgery.
Understanding the population-level costs of preoperative anaemia will inform development and …