The changing face of thyroid cancer in a population‐based cohort

K Alok Pathak, WD Leslie, TC Klonisch… - Cancer …, 2013 - Wiley Online Library
In North America, the incidence of thyroid cancer is increasing by over 6% per year. We studied
the trends and factors influencing thyroid cancer incidence, its clinical presentation, and …

Stage II differentiated thyroid cancer: a mixed bag

KA Pathak, TC Klonisch… - Journal of Surgical …, 2016 - Wiley Online Library
Background and Objectives AJCC‐TNM Stage II well‐differentiated thyroid cancer (WDTC)
comprises T2N0M0 tumors in patients ≥45 years of age or metastatic WDTC in patients …

[HTML][HTML] Canadian Society of Surgical Oncology Nineteenth Annual Scientific MeetingWhat provider volume is appropriate for gastric cancer resection? Results of a …

…, A Mazurat, P Lambert, TC Klonisch… - Canadian Journal of …, 2012 - ncbi.nlm.nih.gov
Background Some studies suggest an inverse relationship between volume and mortality.
Optimal provider volumes for gastric cancer (GC) are unclear. Methods A multidisciplinary …

Expression of mRNA and protein of nucleoproteins during human spermiogenesis.

K Steger, T Klonisch, K Gavenis… - Molecular human …, 1998 - academic.oup.com
The most important event determining the nuclear status of sperm cells is the replacement of
histones by protamines, which are the basic nuclear proteins of mature spermatozoa. A first …

Human cathelicidin LL-37-derived peptide IG-19 confers protection in a murine model of collagen-induced arthritis

…, H Piyadasa, M Bossert, J Uzonna, T Klonisch… - Molecular …, 2014 - Elsevier
Current therapies for autoimmune chronic inflammatory diseases eg rheumatoid arthritis (RA)
include inhibitors of inflammatory cytokines. However, these therapies can result in …

A prospective cohort study to assess the role of FDG-PET in differentiating benign and malignant follicular neoplasms

…, AL Goertzen, RW Nason, T Klonisch… - Annals of Medicine …, 2016 - journals.lww.com
Background: Follicular and Hürthle cell neoplasms are diagnostic challenges. This prospective
study was designed to evaluate the efficacy of [18F]-2-fluoro-2-deoxy-d-glucose (FDG) …

[HTML][HTML] Role of BNIP3 in TNF-induced cell death—TNF upregulates BNIP3 expression

…, GH Bay, S Wesselborg, AJ Halayko, T Klonisch… - … et Biophysica Acta (BBA …, 2009 - Elsevier
Tumor necrosis factor alpha (TNF) is a cytokine that induces caspase-dependent (apoptotic)
and caspase-independent (necrosis-like) cell death in different cells. We used the murine …

Investigations on T cell transmigration in a human skin-on-chip (SoC) model

…, AE Getschman, S Hwang, BF Volkman, T Klonisch… - Lab on a Chip, 2021 - pubs.rsc.org
A microfluidics-based three-dimensional skin-on-chip (SoC) model is developed in this study
to enable quantitative studies of transendothelial and transepithelial migration of human T …

Characterisation of an in vitro system to study maternal communication with spermatozoa

…, T Klonisch, S Hombach-Klonisch… - Reproduction …, 2012 - CSIRO Publishing
… The amplification conditions were 95C for 30 s for DNA denaturation, followed by 55C for
1 min to anneal the primers and 72C for 1 min to extend the primers. These conditions were …

Biodistribution of negatively charged iron oxide nanoparticles (IONPs) in mice and enhanced brain delivery using lysophosphatidic acid (LPA)

…, JA Thliveris, S Hombach-Klonisch, T Klonisch… - … , Biology and Medicine, 2016 - Elsevier
… Thliveris PhD c , Sabine Hombach-Klonisch PhD c , Thomas Klonisch PhD c , Johan van …
then centrifuged at 5400g for 15 min at 4 C. The supernatant fractions (brain parenchyma) were …