The protein Sonic hedgehog (Shh) controls patterning and growth during vertebrate
development. Here we demonstrate that it binds Patched (vPtc), which has been identified as a …

Wnt family members are critical to many developmental processes, and components of the
Wnt signaling pathway have been linked to tumorigenesis in familial and sporadic colon …

Cardiotrophin-1 (CT-1) is a newly isolated cytokine that was identified based on its ability to
induce cardiac myocyte hypertrophy. It is a member of the family of cytokines that includes …

Completely revised by new authors, this Fourth Edition presents 75 patient cases designed
specifically to prepare students for clinical vignettes on the USMLE Step 2. Each case …

Purpose: Moderate deep inspiration breath-hold (mDIBH), using an Active Breathing Control
device, has been used in our clinic since 2002 to reduce cardiac dose for patients receiving …

Introduction to Statistical Investigations, Second Edition provides a unified framework for
explaining variation across study designs and variable types, helping students increase their …

Brain metastases are a challenging manifestation of renal cell carcinoma. We have a limited
understanding of brain metastasis tumor and immune biology, drivers of resistance to …

Anatomical reduction and rigid internal fixation of fractures of the talar neck allow early
mobilization of the ankle and subtalar joints. Forty fresh tali from cadavera were fractured across …

Importance Radical cystectomy is the guidelines-recommended treatment of muscle-invasive
bladder cancer, but a resurgence of trimodal therapy has occurred. Limited comparative …

The algebra-based introductory statistics course is the most popular undergraduate course
in statistics. While there is a general consensus for the content of the curriculum, the recent …