Although the natural history of autoimmune hepatitis (AIH) has been characterized, little is
known about patients who present asymptomatically. Consequently, whether they require …

Medullary carcinomas of the pancreas are a recently described, histologically distinct subset
of poorly differentiated adenocarcinomas that may have a unique pathogenesis and clinical …

Inactivation of deoxyribonucleic acid (DNA) mismatch repair genes, most commonly human
mutL homologue 1 (hMLH1) or human mutS homologue 2 (hMSH2), is a recently described …

Active-site mTOR inhibitors (asTORi) hold great promise for targeting dysregulated mTOR
signaling in cancer. Because of the multifaceted nature of mTORC1 signaling, identification of …

Background and aims: Current endoscopic activity scores for ulcerative colitis (UC) do not
take into account the extent of mucosal inflammation. We have developed a simple …

Importance Chemoradiotherapy (CRT), followed by surgery, is the recommended approach
for stage II and III rectal cancer. While CRT decreases the risk of local recurrence, it does not …

<p id="p001">A patient received a diagnosis of adenocarcinoma of the ampulla of Vater at
34 years of age. Two decades later, adenomatous polyps were found, followed by multiple …

CD98-mediated β1 and β3 integrins activation can induce Fak phosphorylation which
eventually promotes cell survival, proliferation, and migration. We evaluated the expression of …

Cryptosporidiosis, caused by the protozoan parasite Cryptosporidium parvum , can stunt
infant growth and can be lethal in immunocompromised individuals. The most widely used …

Background The management of hepatocellular carcinoma (HCC) is limited by the lack of
adequate screening biomarkers and chemotherapy. In response, there has been much interest …