An erratum for this article appears in the January, 2004 issue of Movement Disorders ( Mov
Disord 2004;19:119 ). Parkinson's disease (PD) is a common neurodegenerative disorder …

1. Introduction 8649 2. The C-ring construction approach 8651 2.1. Comins’s total synthesis
of (þ)-camptothecin and (^)-mappicine 8651 2.2. Glaxo Wellcome’s total synthesis of …

Minocycline mediates neuroprotection in experimental models of neurodegeneration. It
inhibits the activity 1 , 2 , 3 , 4 , 5 , 6 of caspase-1, caspase-3, inducible form of nitric oxide …

Altered degradation of α-synuclein (α-syn) has been implicated in the pathogenesis of
Parkinson disease (PD). We have shown that α-syn can be degraded via chaperone-mediated …

Parkinson's disease (PD) is a neurodegenerative disorder of uncertain pathogenesis
characterized by the loss of the nigrostriatal dopaminergic neurons, which can be modeled by the …

Parkinson's disease (PD) is a neurodegenerative disorder of uncertain pathogenesis
characterized by a loss of substantia nigra pars compacta (SNpc) dopaminergic (DA) neurons, and …

Acute myocardial infarction refers to a sudden death of cardiomyocytes, which leads to a large
mortality worldwide. To attenuate acute myocardial infarction, strategies should be made …

Parkinson disease (PD) is a neurodegenerative disorder characterized by a loss of the
nigrostriatal dopaminergic neurons accompanied by a deficit in mitochondrial respiration. 1-…

Tumor recurrence following treatment remains a major clinical challenge. Evidence from
xenograft models and human trials indicates selective enrichment of cancer-initiating cells (CICs…

Parkinson's disease (PD) is characterized by a loss of ventral midbrain dopaminergic neurons,
which can be modeled by the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (…