Anticancer drug resistance results from selective pressure of chemotherapy, together with
mutations or epigenetic changes that make cells refractory to treatment. In cancer cells, we …

For effectively treating tumor related-bone defects, design and fabrication of multifunctional
biomaterials still remain a great challenge. Herein, we firstly fabricated magnetic SrFe 12 O …

BACKGROUND: Titanium elastic nails (TENs) are commonly used to repair displaced midshaft
clavicular fractures. Although several clinical studies have shown that the use of TENs is …

Background Concentrated leukocytes in leukocyte-and platelet-rich plasma (L-PRP) may
deliver increased levels of pro-inflammatory cytokines to activate the NF-κB signaling pathway, …

Oral or intravenous chemotherapy is an important strategy to treat metastatic cancer, but it
may cause systemic toxicity for healthy tissue. Herein, we for the first time fabricated …

In the last decade, the medial sural artery perforator flap (MSAP) has emerged as one of the
most popular reconstructive options for multiple body sites. The versatility of the flap hinges …

The toxic risks and adverse effects of anticancer drugs on healthy tissues limit their wide
clinical application. Herein, we for the first time fabricated hollow mesoporous ZSM-5/chitosan …

The effects of hypoxia on the osteogenic potential of mesenchymal stem cells (MSCs) have
been previously reported. From these studies, possible factors affecting the association …

Background Midclavicular fractures are common clinically, accounting for about 76% of all
clavicular fractures. Recent studies have revealed a previously unrecognized incidence of …

No satisfactory method currently exists for repairing long peripheral nerve defects. Efforts
have been made to fabricate bioactive artificial nerve conduits, comprised of a biomaterial pre-…