User profiles for Yongtao Lin

Yongtao Lin

Natural Resources Canada
Verified email at canada.ca
Cited by 87

circ‐AKT3 aggravates renal ischaemia‐reperfusion injury via regulating miR‐144‐5p/Wnt/β‐catenin pathway and oxidative stress

…, L Zhong, H Li, L Bai, X Chen, Y Lin… - Journal of Cellular …, 2022 - Wiley Online Library
Renal ischaemia‐reperfusion (RI/R) injury is one major pathological state of acute kidney
injury (AKI) with a mortality rate ranking 50% to 80%. MiR‐144‐5p acts as a molecular trigger …

[HTML][HTML] miR-195-5p alleviates acute kidney injury through repression of inflammation and oxidative stress by targeting vascular endothelial growth factor A

…, W Jiang, L Zhong, H Li, L Bai, X Chen, Y Lin… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Acute kidney injury (AKI) is a common renal dysfunction. Renal ischemia-reperfusion (I/R)
injury contributes to AKI progression. The microRNA miR-195-5p can act as a crucial tumor …

[HTML][HTML] MiR-27b-3p inhibits the progression of renal fibrosis via suppressing STAT1

L Bai, Y Lin, J Xie, Y Zhang, H Wang, D Zheng - Human cell, 2021 - Springer
Renal fibrosis is a pathologic change in chronic kidney disease (CKD). MicroRNAs (miRNAs)
have been shown to play an important role in the development of renal fibrosis. However, …

[HTML][HTML] Curcumin-loaded nanoparticles protect against rhabdomyolysis-induced acute kidney injury

X Chen, J Sun, H Li, H Wang, Y Lin, Y Hu… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Rhabdomyolysis (RM) is a potentially life-threatening condition that results
from the breakdown of muscle and consequent release of toxic compounds into circulation…

Renoprotective effect and mechanism of polysaccharide from Polyporus umbellatus sclerotia on renal fibrosis

H Li, Z Yan, Q Xiong, X Chen, Y Lin, Y Xu, L Bai… - Carbohydrate …, 2019 - Elsevier
As a fungal polysaccharide, polysaccharide (PPUS) from Polyporus umbellatus sclerotia
have showed remarkable anti-inflammatory activities. In view of the closely relationship …

Enantioselective separation of ketoconazole enantiomers by membrane extraction

Z Wang, C Cai, Y Lin, Y Bian, H Guo, X Chen - Separation and purification …, 2011 - Elsevier
A new process has been developed to separate ketoconazole (KTZ) enantiomers by membrane
extraction, with the oppositely preferential recognition of hydrophobic and hydrophilic …

Circ_0023404 sponges miR‐136 to induce HK‐2 cells injury triggered by hypoxia/reoxygenation via up‐regulating IL‐6R

Y Xu, X Li, H Li, L Zhong, Y Lin, J Xie… - Journal of Cellular and …, 2021 - Wiley Online Library
The significance of circular RNAs (circRNAs) is reported in various kidney diseases
including acute kidney injury (AKI). Specific circRNAs have the capacity to function as novel …

[HTML][HTML] Psoralen alleviates high glucose-induced HK-2 cell injury by inhibition of Smad 2 signaling via upregulation of microRNA 874

Y Lin, L Zhong, H Li, Y Xu, X Li, D Zheng - BMC Pharmacology and …, 2020 - Springer
Background Diabetic nephropathy (DN) causes the vast proportion of excess mortality for
patients with diabetes. Novel therapeutic approaches slowing down its incidence is still lacking…

Protective effects of liquiritin on polycystic ovary syndrome through modulating ovarian granulosa cell proliferation and apoptosis via miR-206/PI3K/AKT pathway

X Cui, S Zhou, Y Lin - Cytotechnology, 2022 - Springer
Polycystic ovarian syndrome (PCOS) is a frequent metabolic disorder in premenopausal
woman, featured with increased androgen, reduced ovulation and insulin resistance. An …

[HTML][HTML] Berberine nanoparticles protects tubular epithelial cells from renal ischemia-reperfusion injury

…, W Jing, Z Juxiang, L Hailun, H Yu, DH Zheng, YT Lin - Oncotarget, 2017 - ncbi.nlm.nih.gov
Renal ischemia-reperfusion (I/R) injury is one of the most common causes of acute renal
failure, the prognosis of which remains poor and there still lacks of effective therapeutics …