Object. The extent of tumor resection that should be undertaken in patients with glioblastoma
multiforme (GBM) remains controversial. The purpose of this study was to identify …

Study Design. Systematic review and modified Delphi technique. Objective. To use an
evidence-based medicine process using the best available literature and expert opinion …

Object. The current North American experience with minimally invasive vertebro- and
kyphoplasty is largely limited to the treatment of benign osteoporotic compression fractures. The …

Purpose Standardized indications for treatment of tumor-related spinal instability are hampered
by the lack of a valid and reliable classification system. The objective of this study was to …

Object. Anterior approaches to the spine for the treatment of spinal tumors have gained
acceptance; however, in most published reports, patients with primary, metastatic, or chest wall …

Background: Cervical spondylotic myelopathy is the leading cause of spinal cord
dysfunction worldwide. The objective of this study was to evaluate the impact of surgical …

Stereotactic biopsy is often performed for diagnostic purposes before treating patients whose
imaging studies highly suggest glioma. Indications cited for biopsy include diagnosis and/…

With continued growth of the elderly population and improvements in cancer therapies, the
number of patients with symptomatic spinal metastases is likely to increase, and this is a …

Cell-free DNA shed by cancer cells has been shown to be a rich source of putative tumor-specific
biomarkers. Because cell-free DNA from brain and spinal cord tumors cannot usually …

OBJECTIVE: Sacral chordomas are relatively rare, locally invasive, malignant neoplasms.
Despite surgical resection, adjuvant radiation therapy, and chemotherapy, recurrence is …