The spleen is crucial in regulating immune homoeostasis through its ability to link innate and
adaptive immunity and in protecting against infections. The impairment of splenic function is …

Surgical removal of the spleen, splenectomy, is a procedure that has significantly decreased
in frequency as our understanding of the infectious complications of the asplenic state …

Although preservation of the spleen following abdominal trauma and spleen-preserving
surgical procedures have become gold standards, about 22,000 splenectomies are still …

Splenectomy, while often necessary in otherwise healthy patients after major trauma, finds
its primary indication for patients with underlying malignant or nonmalignant hematologic …

Non-transfusion-dependent thalassemia (NTDT) has been considered less severe than its
transfusion-dependent variants. The most common forms of NTDT include β-thalassemia …

Abstract Background/Purpose In order to avoid consequences of total splenectomy
(including severe postsplenectomy sepsis), partial splenectomy (PS) is increasingly …

Methods From August 2019 to January 2020, serum samples were obtained from 90
persons, 30 of whom were healthy, and 60 (46 male and 44 female) with β-thalassemia …

The spleen is a secondary lymphoid organ that belongs to the reticular-endothelial system,
directly connected to blood circulation. The spleen is greatly involved in the immune …

Background: Iron overload is an important issue in the state of thalassemic patients due to
the harmful effect of high concentration of iron deposited in different tissues in human body …

Background Thalassaemia is a genetic disorder of the haemoglobin protein in red blood
cells. It has been historically classified into thalassaemia minor, intermedia and major …