Rationale Blinding reduces performance and detection bias in randomized controlled trials
(RCT). There is evidence that lack of blinding leads to overestimation of treatment effects in …

Surgical treatments are half as likely as medical therapies to be based on randomized
controlled trial (RCT) evidence. 1 The paucity of randomized surgical trials may reflect …

The application of evidence-based care in the practice of surgery has improved in the past
decade (ie, colorectal surgery, arthroplasty surgery), 1, 2 but surgical treatments are still less …

Aim To present an overview of the main components of randomised controlled trials and
identify issues for consideration during their design and management. Background …

“Where’s the Music?” Using Music Therapy for Pain Management - PMC Back to Top Skip to
main content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main Content …

Introduction: Delirium is a serious issue associated with high morbidity and mortality in older
hospitalised people. Early recognition enables diagnosis and treatment of underlying …

Randomized controlled trials (RCT) are considered as the optimal study design to eliminate
bias and are used frequently by clinicians to guide therapeutic decision-making; however …

Despite years of training and schooling, clinicians routinely encounter difficult clinical
scenarios that go beyond the scope of their everyday practice. To answer such questions …

Prognostic studies examine the effect of variables, like surgical interventions, on disease
progression. When posed with a clinical question around outcomes and prognosis …

Gastroesophageal reflux disease (GERD) is characterized mainly by heartburn and
acidregurgitation but in the more severe forms even organic manifestations can occur …