[HTML][HTML] Recent advances in the investigation of pancreatic inflammation induced by large doses of basic amino acids in rodents
It has been known for approximately 30 years that large doses of the semi-essential basic
amino acid L-arginine induce severe pancreatic inflammation in rats. Recently, it has been …
amino acid L-arginine induce severe pancreatic inflammation in rats. Recently, it has been …
[HTML][HTML] TLR4-mediated NF-κB signaling pathway mediates HMGB1-induced pancreatic injury in mice with severe acute pancreatitis
G Li, X Wu, L Yang, Y He, Y Liu… - International …, 2016 - spandidos-publications.com
Severe acute pancreatitis (SAP) is an extremely dangerous acute abdominal disorder which
causes multiple complications and has a high mortality rate. Previous research has …
causes multiple complications and has a high mortality rate. Previous research has …
[HTML][HTML] Context-dependent epigenetic regulation of nuclear factor of activated T cells 1 in pancreatic plasticity
NM Chen, A Neesse, ML Dyck, B Steuber, AO Koenig… - Gastroenterology, 2017 - Elsevier
Background & Aims The ability of exocrine pancreatic cells to change the cellular phenotype
is required for tissue regeneration upon injury, but also contributes to their malignant …
is required for tissue regeneration upon injury, but also contributes to their malignant …
[HTML][HTML] Genistein attenuated oxidative stress, inflammation, and apoptosis in L-arginine induced acute pancreatitis in mice
P Siriviriyakul, J Sriko, K Somanawat… - … Medicine and Therapies, 2022 - Springer
Aim Acute pancreatitis is a common and potentially serious condition. However, a specific
treatment for this condition is still lacking. Genistein, with its anti-oxidant and anti …
treatment for this condition is still lacking. Genistein, with its anti-oxidant and anti …
Specific lipase-responsive polymer-coated gadolinium nanoparticles for MR imaging of early acute pancreatitis
HW Zhang, LQ Wang, QF Xiang, Q Zhong, LM Chen… - Biomaterials, 2014 - Elsevier
Currently, available methods for diagnosis of acute pancreatitis (AP) are mainly dependent
on serum enzyme analysis and imaging techniques that are too low in sensitivity and …
on serum enzyme analysis and imaging techniques that are too low in sensitivity and …
Eff ects of hemin, a heme oxygenase-1 inducer in L-arginine-induced acute pancreatitis and associated lung injury in adult male albino rats
Objective. The aim of the current study was to assess the protective outcome of hemin, a
heme oxygenase-1 (HO-1) inducer on L-arginine-induced acute pancreatitis in rats. Acute …
heme oxygenase-1 (HO-1) inducer on L-arginine-induced acute pancreatitis in rats. Acute …
Trimetazidine alone or in combination with gemcitabine and/or abraxane decreased cell viability, migration and ATP levels and induced apoptosis of human …
ZA Şekeroğlu, V Şekeroğlu, S Işık, B Aydın - Clinics and Research in …, 2021 - Elsevier
Background Trimetazidine (TMZ) is an anti-ischemic agent that can inhibit the fatty acid
oxidation. It has been stated that inhibition of fatty acid oxidation may be an acceptable …
oxidation. It has been stated that inhibition of fatty acid oxidation may be an acceptable …
The protective effects of trimetazidine against ovary ischemia–reperfusion injury via the TLR4/Nf‐kB signal pathway
Late diagnosis and treatment of ovarian ischemia can lead to worsening of ischemia,
irreversible damage to ovarian functions and infertility. In this process, there is no approved …
irreversible damage to ovarian functions and infertility. In this process, there is no approved …
[HTML][HTML] Vaccinium macrocarpon Aiton Extract Ameliorates Inflammation and Hyperalgesia through Oxidative Stress Inhibition in Experimental Acute Pancreatitis
DG Santana, AS Oliveira, MTS Souza… - Evidence-Based …, 2018 - hindawi.com
We evaluated the effect of the hydroethanolic extract of fruits of Vaccinium macrocarpon
(HEVm) in a model of acute pancreatitis (AP) in mice. AP was induced by two injections of L …
(HEVm) in a model of acute pancreatitis (AP) in mice. AP was induced by two injections of L …
Comparing the preventive effect of sodium hydrosulfide, leptin, and curcumin against L-arginine induced acute pancreatitis in rats: role of corticosterone and inducible …
Objectives. Acute pancreatitis (AP) is a life-threatening condition. Using antioxidants in AP is
insufficient and conflicting. Therefore, this study compared the effect of hydrogen sulfide …
insufficient and conflicting. Therefore, this study compared the effect of hydrogen sulfide …