Background In acute pancreatitis, oxygen free radicals (OFRs) and cytokines have been
shown to play a role in the failure of pancreatic microcirculation and the development of …

This study was aimed at an assessment of the role of oxygen-derived free radicals in the
pathogenesis of L-arginine (Arg)-induced acute pancreatitis in rat, by measuring the levels …

Objective: To assess the effects of inhibiting both tumor necrosis factor (TNF)-α production
and xanthine oxidase activity on the inflammatory response, mitogen-activated protein …

Acute pancreatitis (AP) is an acute inflammatory disorder of the pancreas that can be
complicated by involvement of other remote organs. Oxidative stress is known to have a …

Acute pancreatitis is a sudden inflammation of the pancreas that may be life threatening
disease with high mortality rates; particularly in presence of systemic inflammatory response …

Background: Oxidative stress mediates acinar injury in experimental acute pancreatitis (AP)
and antioxidants are depleted in human AP. This study tests the hypothesis that exogenous …

Background: Acute pancreatitis (AP) is an inflammatory disease, where oxidative stress,
subsequently inflammatory mediators activation play a pivotal role. Currently, no definite …

Materials and Methods Two hundred male Wistar rats were randomly assigned to one of the
following experimental groups. In two groups, acute necrotizing pancreatitis was induced by …

Objective Acute pancreatitis continues to be associated with significant rates of mortality and
morbidity, and therapeutic options are still very limited. We aimed to investigate the efficacy …

AIM: To evaluate the role of microcirculatory disorder (MCD) and the therapeutic
effectiveness of tetramethylpyrazine (TMP) on intestinal mucosa injury in rats with acute …