The effect of epsilon aminocaproic acid on blood loss in patients who undergo primary total hip
replacement: a pilot study - PMC Back to Top Skip to main content NIH NLM Logo Access keys …

A prospective randomized double‐blind placebo‐controlled study was undertaken to
determine the efficacy and mechanism of action of two antifibrinolytic drugs aprotinin and …

Purpose To evaluate the peri-operative blood loss with the use of epsilon-aminocaproic acid
(ε-ACA) in total hip arthroplasty (THA). Methods One hundred sixty patients treated with THA …

Background Use of antifibrinolytic agents in total hip arthroplasty (THA) is well supported;
however, most studies used tranexamic acid (TXA), whereas few used ε-aminocaproic acid …

Total hip and knee arthroplasties may be associated with a significant amount of
perioperative blood loss. The severity of blood loss may be great enough to require the use …

Background Total hip and knee arthroplasty (THA and TKA) are associated with significant
blood loss and some patients require postoperative blood transfusion. While tranexamic …

Two recent studies have shown decreased blood loss in patients given aprotinin undergoing
primary hip replacement surgery. Because patients undergoing bilateral (bTHA) or revision …

In this prospective, randomised, double-blind study, we investigated the effect of epidural
anaesthesia and an antifibrinolytic agent, Aprotinin (500,000 KIU in bolus before surgery …

BACKGROUND: Epsilon-aminocaproic acid is a plasmin inhibitor that potentially reduces
perioperative bleeding when administered prophylactically to cardiac surgery patients. To …

Introduction Tranexamic acid is an inhibitor of fibrinolysis and thereby decreases blood loss
in patients undergoing surgery. Materials and methods Fifty patients were randomized to …