Discussion Conservative treatment of CSF leakage through a surgical incision usually
involves a combination of pressure dressings, sutures, adhesive tapes, bed rest and head …

Cerebrospinal fluid (CSF) leak is an adverse event that can affect the postoperative course
of neurosurgical patients. Despite the large intra-operative use effective strategies as well as …

Objective: Persistent cerebrospinal fluid leaks in the human population are rarely found in
otherwise healthy individuals, but occur in patients with comorbid illnesses. These leaks are …

OBJECTIVE: The in vitro stability of fibrin sealant in cerebrospinal fluid (CSF) was
investigated to verify the efficacy of intracranial application of fibrin sealant. METHODS …

OBJECTIVE: To determine the clinical efficacy and cost effectiveness of using the fibrin
sealant (FS) Tisseel (Baxter Healthcare Corp., Deerfield, IL) for patients undergoing anterior …

OBJECTIVE: This report evaluates the sealing effects of firin sealant applied on the dura
mater using different techniques. METHODS: Three application methods were studied: a …

Background Cerebrospinal fluid (CSF) leak remains a significant source of morbidity after
neurosurgical procedures. The objective is to evaluate the effectiveness and safety of a …

OBJECTIVE The effectiveness of a strong, pressure-tight method for fibrin sealant
application was experimentally and clinically evaluated, using expanded …

This is a comment on" Prospective randomized multicenter trial of fibrin sealant versus
thrombin-soaked gelatin sponge for suture-or needle-hole bleeding from …

Cerebrospinal fluid leakage is one of the central problems facing neurosurgeons, both due
to its occasional difficulty in management and to the catastrophical significance of ensuing …