Background: It has recently been reported that mismatch repair (MMR) status and
microsatellite instability (MSI) status in gastroesophageal carcinomas predict surgical …

Background Reliability of mismatch repair proteins and microsatellite instability assessment
is essential in order to define treatment strategy and identify candidates to immune …

Background and objectives Evidence is inconclusive regarding the prognostic significance
of deficient DNA mismatch repair (dMMR) in gastric and gastroesophageal junction (GEJ) …

Gastroesophageal cancers are a major cause of death worldwide and treatment outcomes
remain poor. Adequate predictive biomarkers have not been identified. Microsatellite …

Esophageal, gastroesophageal junction, and gastric adenocarcinomas, referred to
collectively as gastroesophageal adenocarcinomas (GEAs), are a major cause of global …

Background The use of neoadjuvant chemotherapy (NAC) in patients with mismatch repair
(MMR) deficient (dMMR) localized gastric and oeso-gastric junction (OGJ) adenocarcinoma …

Objective The predictive value of mismatch repair protein deficiency (MMRD) for
chemoradiotherapeutic outcome has rarely been reported in gastric cancer. This study …

Abstracts Background Microsatellite instability (MSI) is a negative predictive factor for
neoadjuvant chemotherapy in resectable oesogastric adenocarcinoma and a crucial …

Introduction To date, the role of deficient mismatch repair (dMMR) remains to be proven in
gastric cancer, and it is difficult to judge its value in clinical application. Our study aimed to …

Background The DNA mismatch repair system is one of the defense mechanisms in the
body, and the inactivation of mismatch repair plays a pivotal role in secondary …