DISCUSSION Neuroendocrine tumours are a distinct subset of neoplasms that manifest in
different organs but share various morphologic, ultrastructural, immunohistochemical and …

PURPOSE: Our goal was to define the incidence of neuroendocrine carcinomas of the colon
and rectum, the patterns of neuroendocrine expression, and the cellular subtype within …

PURPOSE: This study was designed to review experience with neuroendocrine carcinomas
of the colon and rectum at a single institution, with emphasis on the pathology and clinical …

Neuroendocrine carcinomas were diagnosed in 13 of 683 patients who had colon cancers
removed from January 1980 to June 1987 for an incidence of 1.9%. The patients were 28 to …

Neuroendocrine tumors (NETs) are a heterogeneous group of malignancies arising from
neural crest-derived cells throughout the body. The presentation and natural history of NETs …

Neuroendocrine cell tumors of the colon and rectum are divided into two groups: carcinoid
tumors with low-grade atypia and malignancy; and endocrine cell carcinomas (ECCs) with …

The first description of a small bowel neuroendocrine tumor (SBNET) was by Theodor
Langhans, who in 1867 reported a polypoid tumor of the small bowel discovered on …

To further characterize the clinicopathologic spectrum of colorectal neuroendocrine
neoplasia, 24 carcinomas with neuroendocrine differentiation were subtyped as either small …

Three patients are described who presented with a large colonic adenoma in which a solid,
undifferentiated carcinomatous component was found on microscopic examination. Despite …

Large cell neuroendocrine carcinomas are rare and aggressive colorectal malignancies that
have a dismal prognosis. We present the following case of a patient who presented with …